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Slc35b1 solute carrier family 35, member B1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287642, updated on 27-Nov-2024

Summary

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Official Symbol
Slc35b1provided by RGD
Official Full Name
solute carrier family 35, member B1provided by RGD
Primary source
RGD:727783
See related
EnsemblRapid:ENSRNOG00000004510 AllianceGenome:RGD:727783
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
AXER; UGTrel1
Summary
Predicted to enable ATP:ADP antiporter activity; UDP-galactose transmembrane transporter activity; and UDP-glucose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Orthologous to human SLC35B1 (solute carrier family 35 member B1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 278.0), Kidney (RPKM 275.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Slc35b1 in Genome Data Viewer
Location:
10q26
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (80824972..80832048)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (80327921..80335279)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (83201532..83208605)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102546674 Neighboring gene family with sequence similarity 117, member A Neighboring gene uncharacterized LOC120095178 Neighboring gene speckle type BTB/POZ protein Neighboring gene small nucleolar RNA SNORA4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Molecular cloning and characterization of a novel isoform of the human UDP-galactose transporter, and of related complementary DNAs belonging to the nucleotide-sugar transporter gene family. Ishida N, et al. J Biochem, 1996 Dec. PMID 9010752
  2. Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment. Lee NH, et al. Proc Natl Acad Sci U S A, 1995 Aug 29. PMID 7667285, Free PMC Article
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC105266

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP:ADP antiporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP:ADP antiporter activity ISO
Inferred from Sequence Orthology
more info
  
enables UDP-galactose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glucose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ADP transport IEA
Inferred from Electronic Annotation
more info
  
involved_in ATP transport IEA
Inferred from Electronic Annotation
more info
  
involved_in UDP-galactose transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in UDP-glucose transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
solute carrier family 35 member B1
Names
ATP/ADP exchanger ER
UDP-galactose transporter-related protein 1
endoplasmic reticulum ATP/ADP translocase
galactose transporter

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199081.1 → NP_954512.1  solute carrier family 35 member B1

    See identical proteins and their annotated locations for NP_954512.1

    Status: PROVISIONAL

    Source sequence(s)
    AY349135
    UniProtKB/Swiss-Prot
    P70639, Q6V7K3
    UniProtKB/TrEMBL
    A0A8I6ADT8
    Related
    ENSRNOP00000006179.3, ENSRNOT00000006179.6
    Conserved Domains (1) summary
    pfam08449
    Location:16 → 309
    UAA; UAA transporter family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    80824972..80832048
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039085590.2 → XP_038941518.1  solute carrier family 35 member B1 isoform X2

    Conserved Domains (1) summary
    pfam08449
    Location:1 → 212
    UAA; UAA transporter family

  2. XM_039085591.2 → XP_038941519.1  solute carrier family 35 member B1 isoform X1

    Conserved Domains (1) summary
    pfam08449
    Location:1 → 185
    UAA; UAA transporter family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6V7K3.1 GenPept UniProtKB/Swiss-Prot:Q6V7K3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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