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Rsph10b radial spoke head 10 homolog B [ Rattus norvegicus (Norway rat) ]

Gene ID: 288478, updated on 4-Jan-2025

Summary

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Official Symbol
Rsph10bprovided by RGD
Official Full Name
radial spoke head 10 homolog Bprovided by RGD
Primary source
RGD:1311893
See related
EnsemblRapid:ENSRNOG00000001036 AllianceGenome:RGD:1311893
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311893
Summary
Predicted to be located in 9+2 motile cilium. Orthologous to several human genes including RSPH10B (radial spoke head 10 homolog B). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Testes (RPKM 134.1), Lung (RPKM 50.8) and 2 other tissues See more
Orthologs
human all
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Genomic context

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See Rsph10b in Genome Data Viewer
Location:
12p11
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (15741097..15788887, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (10627434..10675227, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (12665194..12713834, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene elongation factor 1-gamma-like Neighboring gene oncomodulin Neighboring gene CCZ1 homolog, vacuolar protein trafficking and biogenesis associated Neighboring gene small nucleolar RNA SNORA51 Neighboring gene PMS1 homolog 2, mismatch repair system component Neighboring gene aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in 9+2 motile cilium ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in axoneme IEA
Inferred from Electronic Annotation
more info
  
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
radial spoke head 10 homolog B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013867.1 → NP_001013889.1  radial spoke head 10 homolog B

    See identical proteins and their annotated locations for NP_001013889.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081935
    UniProtKB/Swiss-Prot
    Q66HB5
    Related
    ENSRNOP00000102642.1, ENSRNOT00000159819.1
    Conserved Domains (3) summary
    smart00698
    Location:225 → 244
    MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
    COG4642
    Location:122 → 334
    COG4642; Uncharacterized conserved protein [Function unknown]
    pfam02493
    Location:109 → 129
    MORN; MORN repeat

  2. NM_001433437.1 → NP_001420366.1  radial spoke head 10 homolog B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/Swiss-Prot
    Q66HB5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    15741097..15788887 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063271137.1 → XP_063127207.1  radial spoke head 10 homolog B isoform X4

  2. XM_006248859.5 → XP_006248921.1  radial spoke head 10 homolog B isoform X1

    See identical proteins and their annotated locations for XP_006248921.1

    Related
    ENSRNOP00000037688.6, ENSRNOT00000034483.8
    Conserved Domains (1) summary
    PLN03185
    Location:158 → 421
    PLN03185; phosphatidylinositol phosphate kinase; Provisional

  3. XM_006248860.5 → XP_006248922.1  radial spoke head 10 homolog B isoform X2

    Conserved Domains (3) summary
    smart00698
    Location:255 → 274
    MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
    COG4642
    Location:152 → 364
    COG4642; Uncharacterized conserved protein [Function unknown]
    pfam02493
    Location:140 → 159
    MORN; MORN repeat

  4. XM_006248858.5 → XP_006248920.1  radial spoke head 10 homolog B isoform X1

    See identical proteins and their annotated locations for XP_006248920.1

    Conserved Domains (1) summary
    PLN03185
    Location:158 → 421
    PLN03185; phosphatidylinositol phosphate kinase; Provisional

  5. XM_063271136.1 → XP_063127206.1  radial spoke head 10 homolog B isoform X4

  6. XM_006248861.5 → XP_006248923.1  radial spoke head 10 homolog B isoform X3

    Conserved Domains (3) summary
    smart00698
    Location:225 → 244
    MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
    COG4642
    Location:122 → 334
    COG4642; Uncharacterized conserved protein [Function unknown]
    pfam02493
    Location:109 → 129
    MORN; MORN repeat

  7. XM_063271138.1 → XP_063127208.1  radial spoke head 10 homolog B isoform X4

  8. XM_063271135.1 → XP_063127205.1  radial spoke head 10 homolog B isoform X3

    UniProtKB/Swiss-Prot
    Q66HB5

  9. XM_039089176.2 → XP_038945104.1  radial spoke head 10 homolog B isoform X1

    Conserved Domains (1) summary
    PLN03185
    Location:158 → 421
    PLN03185; phosphatidylinositol phosphate kinase; Provisional
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q66HB5.1 GenPept UniProtKB/Swiss-Prot:Q66HB5

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