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Spata24 spermatogenesis associated 24 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291676, updated on 27-Nov-2024

Summary

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Official Symbol
Spata24provided by RGD
Official Full Name
spermatogenesis associated 24provided by RGD
Primary source
RGD:1311742
See related
AllianceGenome:RGD:1311742
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311742
Summary
Predicted to enable DNA binding activity and identical protein binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in cytosol; male germ cell nucleus; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human SPATA24 (spermatogenesis associated 24). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 854.1), Heart (RPKM 47.5) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Spata24 in Genome Data Viewer
Location:
18p11
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (27523133..27531375, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (27249047..27257129, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (28446592..28454724, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene marginal zone B and B1 cell-specific protein Neighboring gene proline-rich basic protein 1 Neighboring gene DnaJ heat shock protein family (Hsp40) member C18 Neighboring gene endothelial cell surface expressed chemotaxis and apoptosis regulator

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Cloning and characterization of a novel spermiogenesis-related gene, T6441, in rat testis. Song XX, et al. Front Biosci, 2006 Jan 1. PMID 16146721
  2. TIPT, a male germ cell-specific partner of TRF2, is chromatin-associated and interacts with HP1. Brancorsini S, et al. Cell Cycle, 2008 May 15. PMID 18418073
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the T6441 gene may play a role in cytoplasm movement and removal during spermiogenesis
    Title: Cloning and characterization of a novel spermiogenesis-related gene, T6441, in rat testis.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in male germ cell nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
spermatogenesis-associated protein 24
Names
testis protein T6441

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025636.2 → NP_001020807.2  spermatogenesis-associated protein 24

    See identical proteins and their annotated locations for NP_001020807.2

    Status: VALIDATED

    Source sequence(s)
    BQ207964, CR463891, DQ080016
    UniProtKB/TrEMBL
    A6J2Z1
    Conserved Domains (1) summary
    pfam15175
    Location:25 → 128
    SPATA24; Spermatogenesis-associated protein 24

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    27523133..27531375 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006254545.5 → XP_006254607.1  spermatogenesis-associated protein 24 isoform X1

    See identical proteins and their annotated locations for XP_006254607.1

    UniProtKB/Swiss-Prot
    D3ZAG4, Q4PJT6
    Conserved Domains (1) summary
    pfam15175
    Location:22 → 191
    SPATA24; Spermatogenesis-associated protein 24

  2. XM_039096723.2 → XP_038952651.1  spermatogenesis-associated protein 24 isoform X2

    Conserved Domains (1) summary
    pfam15175
    Location:22 → 128
    SPATA24; Spermatogenesis-associated protein 24
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4PJT6.3 GenPept UniProtKB/Swiss-Prot:Q4PJT6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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