Abhd3 abhydrolase domain containing 3, phospholipase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Abhd3provided by RGD
Official Full Name: abhydrolase domain containing 3, phospholipaseprovided by RGD
Primary source: RGD:1310655
See related: EnsemblRapid:ENSRNOG00000029370 AllianceGenome:RGD:1310655
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable carboxylic ester hydrolase activity. Predicted to be involved in medium-chain fatty acid biosynthetic process; medium-chain fatty acid catabolic process; and phosphatidylcholine metabolic process. Predicted to be located in membrane. Orthologous to human ABHD3 (abhydrolase domain containing 3, phospholipase). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Adrenal (RPKM 938.0), Brain (RPKM 314.5) and 1 other tissue See more
Orthologs: human mouse all
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Genomic context

Location:: 18p13

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (1996010..2051311, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (1723203..1778488, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (1892413..1946840, complement)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables acetylesterase activity	IBA Inferred from Biological aspect of Ancestor more info
enables monoacylglycerol lipase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phospholipase A1 activity	IBA Inferred from Biological aspect of Ancestor more info
enables phospholipase A1 activity	ISO Inferred from Sequence Orthology more info
enables phospholipase A2 activity	IBA Inferred from Biological aspect of Ancestor more info
enables phospholipase A2 activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in medium-chain fatty acid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in medium-chain fatty acid catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in phosphatidylcholine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in phosphatidylcholine metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: phospholipase ABHD3

Names: abhydrolase domain-containing protein 3

NP_001099632.1

EC 3.1.1.32

EC 3.1.1.4

XP_063133339.1

EC 3.1.1.32

EC 3.1.1.4

XP_063133340.1

EC 3.1.1.32

EC 3.1.1.4

XP_063133341.1

EC 3.1.1.32

EC 3.1.1.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.