U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp606 zinc finger protein 606 [ Rattus norvegicus (Norway rat) ]

Gene ID: 292610, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
Zfp606provided by RGD
Official Full Name
zinc finger protein 606provided by RGD
Primary source
RGD:1309810
See related
AllianceGenome:RGD:1309810
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Znf606
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZNF606 (zinc finger protein 606). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Muscle (RPKM 78.4), Heart (RPKM 78.4) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Zfp606 in Genome Data Viewer
Location:
1q21
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (82054118..82097574)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (72981920..73022423)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (66229845..66256901, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor pseudogene 64 Neighboring gene vomeronasal 2 receptor, pseudogene 59 Neighboring gene uncharacterized LOC120099764 Neighboring gene uncharacterized LOC120099762 Neighboring gene similar to human chromosome 19 open reading frame 18 Neighboring gene vomeronasal 2 receptor, pseudogene 60 Neighboring gene vomeronasal 2 receptor, 33

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A novel profile of expressed sequence tags for zinc finger encoding genes from the poorly differentiated exocrine pancreatic cell line AR4IP. Gebelein B, et al. Cancer Lett, 1996 Aug 2. PMID 8697448
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein 606

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001432048.1 → NP_001418977.1  zinc finger protein 606 isoform a

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6KQN5, G3V8H6

  2. NM_001432049.1 → NP_001418978.1  zinc finger protein 606 isoform a

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6KQN5, G3V8H6

  3. NM_001432050.1 → NP_001418979.1  zinc finger protein 606 isoform b

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

  4. NM_001432051.1 → NP_001418980.1  zinc finger protein 606 isoform b

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

  5. NM_001432052.1 → NP_001418981.1  zinc finger protein 606 isoform b

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

  6. NM_001432054.1 → NP_001418983.1  zinc finger protein 606 isoform c

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

  7. NM_001432056.1 → NP_001418985.1  zinc finger protein 606 isoform d

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

  8. NM_001432057.1 → NP_001418986.1  zinc finger protein 606 isoform d

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

  9. NM_001432058.1 → NP_001418987.1  zinc finger protein 606 isoform e

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

  10. NM_001432059.1 → NP_001418988.1  zinc finger protein 606 isoform e

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    82054118..82097574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228139.5 → XP_006228201.1  zinc finger protein 606 isoform X2

    Conserved Domains (3) summary
    smart00349
    Location:44 → 103
    KRAB; krueppel associated box
    COG5048
    Location:373 → 772
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:441 → 461
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_039100665.2 → XP_038956593.1  zinc finger protein 606 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:57 → 116
    KRAB; krueppel associated box
    COG5048
    Location:386 → 785
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:454 → 474
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_039100670.2 → XP_038956598.1  zinc finger protein 606 isoform X2

    Conserved Domains (3) summary
    smart00349
    Location:44 → 103
    KRAB; krueppel associated box
    COG5048
    Location:373 → 772
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:441 → 461
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_063277354.1 → XP_063133424.1  zinc finger protein 606 isoform X3

  5. XM_063277356.1 → XP_063133426.1  zinc finger protein 606 isoform X4

  6. XM_039100667.2 → XP_038956595.1  zinc finger protein 606 isoform X1

    UniProtKB/TrEMBL
    A6KQN5, G3V8H6
    Conserved Domains (3) summary
    smart00349
    Location:57 → 116
    KRAB; krueppel associated box
    COG5048
    Location:386 → 785
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:454 → 474
    ZF_C2H2; C2H2 Zn finger [structural motif]

  7. XM_063277328.1 → XP_063133398.1  zinc finger protein 606 isoform X1

RNA

  1. XR_010059571.1 RNA Sequence

  2. XR_010059570.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools