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Tmem145 transmembrane protein 145 [ Rattus norvegicus (Norway rat) ]

Gene ID: 292722, updated on 9-Dec-2024

Summary

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Official Symbol
Tmem145provided by RGD
Official Full Name
transmembrane protein 145provided by RGD
Primary source
RGD:1595911
See related
EnsemblRapid:ENSRNOG00000020489 AllianceGenome:RGD:1595911
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be located in membrane. Orthologous to human TMEM145 (transmembrane protein 145). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Brain (RPKM 36.1) and Testes (RPKM 17.0) See more
Orthologs
human mouse all
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Genomic context

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See Tmem145 in Genome Data Viewer
Location:
1q21
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (90019727..90029432)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (80891888..80901615)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (82174379..82184075)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 Neighboring gene proline rich 19 Neighboring gene uncharacterized LOC134482973 Neighboring gene multiple EGF-like-domains 8 Neighboring gene uncharacterized LOC120096895 Neighboring gene cornifelin Neighboring gene lipase E, hormone sensitive type

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in response to pheromone IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 145

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001432082.1 → NP_001419011.1  transmembrane protein 145 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6J953

RNA

  1. NR_197264.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    90019727..90029432
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039093582.2 → XP_038949510.1  transmembrane protein 145 isoform X1

    UniProtKB/TrEMBL
    A6J953, D3Z9I0
    Related
    ENSRNOP00000109075.1, ENSRNOT00000170518.1
    Conserved Domains (2) summary
    PHA03247
    Location:434 → 603
    PHA03247; large tegument protein UL36; Provisional
    pfam10192
    Location:157 → 411
    GpcrRhopsn4; Rhodopsin-like GPCR transmembrane domain

  2. XM_002728703.6 → XP_002728749.1  transmembrane protein 145 isoform X2

    Related
    ENSRNOP00000027783.7, ENSRNOT00000027783.7
    Conserved Domains (1) summary
    pfam10192
    Location:157 → 411
    GpcrRhopsn4; Rhodopsin-like GPCR transmembrane domain

  3. XM_063277664.1 → XP_063133734.1  transmembrane protein 145 isoform X3

  4. XM_063277665.1 → XP_063133735.1  transmembrane protein 145 isoform X3

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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