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Lin37 lin-37 DREAM MuvB core complex component [ Rattus norvegicus (Norway rat) ]

Gene ID: 292787, updated on 4-Jan-2025

Summary

Official Symbol
Lin37provided by RGD
Official Full Name
lin-37 DREAM MuvB core complex componentprovided by RGD
Primary source
RGD:1308901
See related
EnsemblRapid:ENSRNOG00000020929 AllianceGenome:RGD:1308901
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308901
Summary
Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be part of Myb complex. Orthologous to human LIN37 (lin-37 DREAM MuvB core complex component). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Heart (RPKM 601.3), Muscle (RPKM 540.7) and 9 other tissues See more
Orthologs
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Genomic context

See Lin37 in Genome Data Viewer
Location:
1q21
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (94936512..94940444, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (85809065..85813235, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (89010254..89014481, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097050 Neighboring gene proline and serine rich 3 Neighboring gene heat shock protein family B (small) member 6 Neighboring gene presenilin enhancer gamma secretase subunit Neighboring gene U2 small nuclear RNA auxiliary factor 1-like 4 Neighboring gene IGF-like family receptor 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of Myb complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of transcription repressor complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein lin-37 homolog
Names
lin-37 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106245.1NP_001099715.1  protein lin-37 homolog

    See identical proteins and their annotated locations for NP_001099715.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473979
    UniProtKB/TrEMBL
    A6J9Y6, D4A503
    Related
    ENSRNOP00000028413.6, ENSRNOT00000028413.7
    Conserved Domains (1) summary
    pfam15306
    Location:84240
    LIN37

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    94936512..94940444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)