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Snx15 sorting nexin 15 [ Rattus norvegicus (Norway rat) ]

Gene ID: 293691, updated on 27-Nov-2024

Summary

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Official Symbol
Snx15provided by RGD
Official Full Name
sorting nexin 15provided by RGD
Primary source
RGD:1305803
See related
EnsemblRapid:ENSRNOG00000021007 AllianceGenome:RGD:1305803
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in protein transport. Predicted to be located in cytosol; nucleolus; and plasma membrane. Orthologous to human SNX15 (sorting nexin 15). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 47.6), Kidney (RPKM 47.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Snx15 in Genome Data Viewer
Location:
1q43
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (212846308..212855450, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (203417029..203426173, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (221487058..221496200, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene cell division cycle associated 5 Neighboring gene N-acetylated alpha-linked acidic dipeptidase-like 1 Neighboring gene uncharacterized LOC120097396 Neighboring gene SAC3 domain containing 1 Neighboring gene uncharacterized LOC134483958 Neighboring gene ARF like GTPase 2 Neighboring gene basic leucine zipper ATF-like transcription factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasmic vesicle membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
sorting nexin-15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024752.1 → NP_001019923.1  sorting nexin-15

    See identical proteins and their annotated locations for NP_001019923.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097481
    UniProtKB/Swiss-Prot
    Q4V896
    UniProtKB/TrEMBL
    A0A8L2QH23, A6HZE5
    Related
    ENSRNOP00000028511.6, ENSRNOT00000028511.9
    Conserved Domains (2) summary
    cd02677
    Location:268 → 338
    MIT_SNX15; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in sorting nexin 15 and related proteins. The molecular function of the MIT domain is unclear.
    cl02563
    Location:10 → 127
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    212846308..212855450 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4V896.1 GenPept UniProtKB/Swiss-Prot:Q4V896

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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