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Bdp1 BDP1 general transcription factor IIIB subunit [ Rattus norvegicus (Norway rat) ]

Gene ID: 294687, updated on 4-Jan-2025

Summary

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Official Symbol
Bdp1provided by RGD
Official Full Name
BDP1 general transcription factor IIIB subunitprovided by RGD
Primary source
RGD:1308512
See related
EnsemblRapid:ENSRNOG00000017864 AllianceGenome:RGD:1308512
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable TFIIIC-class transcription factor complex binding activity. Predicted to be involved in RNA polymerase III preinitiation complex assembly. Predicted to be located in nucleoplasm. Predicted to be part of transcription factor TFIIIB complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 112. Orthologous to human BDP1 (BDP1 general transcription factor IIIB subunit). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 132.1), Spleen (RPKM 102.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Bdp1 in Genome Data Viewer
Location:
2q12
Exon count:
39
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (33112518..33204270, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (31378407..31470140, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (30248458..30340211, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene CART prepropeptide Neighboring gene methylcrotonyl-CoA carboxylase subunit 2 Neighboring gene uncharacterized LOC120100687 Neighboring gene small EDRK-rich factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A structural perspective on RNA polymerase I and RNA polymerase III transcription machineries. Vannini A. Biochim Biophys Acta, 2013 Mar-Apr. PMID 23031840
  2. Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription. Dumay-Odelot H, et al. Cell Cycle, 2010 Sep 15. PMID 20890107, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables TFIIIC-class transcription factor complex binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in RNA polymerase III preinitiation complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
part_of transcription factor TFIIIB complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
transcription factor TFIIIB component B'' homolog
Names
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199195.2 → NP_001186124.1  transcription factor TFIIIB component B'' homolog isoform 2

    See identical proteins and their annotated locations for NP_001186124.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    B2RZ11
    Conserved Domains (1) summary
    pfam15087
    Location:60 → 164
    DUF4551; Protein of unknown function (DUF4551)

  2. NM_001402161.1 → NP_001389090.1  transcription factor TFIIIB component B'' homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    33112518..33204270 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281495.1 → XP_063137565.1  transcription factor TFIIIB component B'' homolog isoform X1

    UniProtKB/TrEMBL
    D3ZDI4
    Related
    ENSRNOP00000024023.7, ENSRNOT00000024023.9

  2. XM_063281496.1 → XP_063137566.1  transcription factor TFIIIB component B'' homolog isoform X2

    Related
    ENSRNOP00000099095.1, ENSRNOT00000130376.1

  3. XM_063281497.1 → XP_063137567.1  transcription factor TFIIIB component B'' homolog isoform X3

  4. XM_063281498.1 → XP_063137568.1  transcription factor TFIIIB component B'' homolog isoform X4

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001106403.1: Suppressed sequence

    Description
    NM_001106403.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: BDP1 (GeneID:55814).
Nucleotide Protein Strain
Heading Accession and Version

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