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Mnd1 meiotic nuclear divisions 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 295160, updated on 4-Jan-2025

Summary

Official Symbol
Mnd1provided by RGD
Official Full Name
meiotic nuclear divisions 1provided by RGD
Primary source
RGD:1309007
See related
EnsemblRapid:ENSRNOG00000024733 AllianceGenome:RGD:1309007
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309007
Summary
Predicted to enable double-stranded DNA binding activity. Predicted to be involved in homologous chromosome pairing at meiosis and reciprocal meiotic recombination. Predicted to be located in nucleus. Orthologous to human MND1 (meiotic nuclear divisions 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 17.1), Testes (RPKM 15.9) and 9 other tissues See more
Orthologs
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Genomic context

See Mnd1 in Genome Data Viewer
Location:
2q34
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (171731523..171794124, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (169433523..169496081, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (183073029..183140768, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485933 Neighboring gene peflin pseudogene Neighboring gene tripartite motif-containing 2 Neighboring gene uncharacterized LOC102550635 Neighboring gene uncharacterized LOC134485931

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in homologous chromosome pairing at meiosis ISO
Inferred from Sequence Orthology
more info
 
involved_in reciprocal meiotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in reciprocal meiotic recombination ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
meiotic nuclear division protein 1 homolog
Names
meiotic nuclear divisions 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398663.1NP_001385592.1  meiotic nuclear division protein 1 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    F1LWN6
    Related
    ENSRNOP00000034074.5, ENSRNOT00000031179.7
    Conserved Domains (1) summary
    COG5124
    Location:5204
    COG5124; Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    171731523..171794124 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281594.1XP_063137664.1  meiotic nuclear division protein 1 homolog isoform X3

  2. XM_063281592.1XP_063137662.1  meiotic nuclear division protein 1 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQ57, A6J5W1
  3. XM_063281593.1XP_063137663.1  meiotic nuclear division protein 1 homolog isoform X2

  4. XM_063281595.1XP_063137665.1  meiotic nuclear division protein 1 homolog isoform X4