Lgals7 galectin 7 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lgals7provided by RGD
Official Full Name: galectin 7provided by RGD
Primary source: RGD:61951
See related: EnsemblRapid:ENSRNOG00000020380 AllianceGenome:RGD:61951
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable carbohydrate binding activity. Predicted to be involved in apoptotic process. Predicted to be located in cytoplasm; extracellular region; and nucleus. Predicted to be active in cornified envelope. Orthologous to several human genes including LGALS7 (galectin 7). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Lung (RPKM 37.9), Muscle (RPKM 4.8) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q21

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (93275092..93279529)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (84148612..84152016)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (87044823..87047223)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Ultrasoundtargeted microbubble destructionmediated Galectin7siRNA promotes the homing of bone marrow mesenchymal stem cells to alleviate acute myocardial infarction in rats.
Title: Ultrasound‑targeted microbubble destruction‑mediated Galectin‑7‑siRNA promotes the homing of bone marrow mesenchymal stem cells to alleviate acute myocardial infarction in rats.
Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.
Title: Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables carbohydrate binding	IBA Inferred from Biological aspect of Ancestor more info
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in apoptotic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cornified envelope	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: galectin-7

Names: gal-7; lectin, galactose binding, soluble 7; lectin, galactoside-binding, soluble, 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_022582.2 → NP_072104.2 galectin-7

See identical proteins and their annotated locations for NP_072104.2

Status: VALIDATED

Source sequence(s)

BI278774, U67883

UniProtKB/Swiss-Prot

O54958, P97590

UniProtKB/TrEMBL

A6J9L7, F8WG95

Related

ENSRNOP00000027620.5, ENSRNOT00000027620.7

Conserved Domains (1) summary

pfam00337
Location:5 → 135

Gal-bind_lectin; Galactoside-binding lectin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

93275092..93279529

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039109505.2 → XP_038965433.1 galectin-7 isoform X1

UniProtKB/Swiss-Prot

O54958, P97590

UniProtKB/TrEMBL

A6J9L7, F8WG95

Conserved Domains (1) summary

pfam00337
Location:5 → 135

Gal-bind_lectin; Galactoside-binding lectin
XM_039109509.2 → XP_038965437.1 galectin-7 isoform X1

UniProtKB/Swiss-Prot

O54958, P97590

UniProtKB/TrEMBL

A6J9L7, F8WG95

Conserved Domains (1) summary

pfam00337
Location:5 → 135

Gal-bind_lectin; Galactoside-binding lectin