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Slc50a1 solute carrier family 50 member 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 295245, updated on 4-Jan-2025

Summary

Official Symbol
Slc50a1provided by RGD
Official Full Name
solute carrier family 50 member 1provided by RGD
Primary source
RGD:1308478
See related
EnsemblRapid:ENSRNOG00000020554 AllianceGenome:RGD:1308478
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rag1ap1; RGD1308478
Summary
Predicted to enable glucoside transmembrane transporter activity and sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport. Located in endomembrane system. Orthologous to human SLC50A1 (solute carrier family 50 member 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Lung (RPKM 78.3), Adrenal (RPKM 76.9) and 9 other tissues See more
Orthologs
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Genomic context

See Slc50a1 in Genome Data Viewer
Location:
2q34
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176975744..176978124, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (174677985..174680366, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (188585118..188587498, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 46 Neighboring gene keratinocyte associated protein 2 Neighboring gene dolichyl-phosphate mannosyltransferase subunit 3, regulatory Neighboring gene ephrin A1 Neighboring gene uncharacterized LOC102550325

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables glucoside transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sugar transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sugar transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in carbohydrate transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in glucoside transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in endomembrane system IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
sugar transporter SWEET1
Names
RAG1-activating protein 1
recombination activating gene 1 activating protein 1
solute carrier family 50 (sugar efflux transporter), member 1
solute carrier family 50 (sugar transporter), member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106445.1NP_001099915.1  sugar transporter SWEET1 precursor

    See identical proteins and their annotated locations for NP_001099915.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473976
    UniProtKB/Swiss-Prot
    D3ZH22
    UniProtKB/TrEMBL
    A6J6E2
    Related
    ENSRNOP00000085247.2, ENSRNOT00000098754.2
    Conserved Domains (1) summary
    pfam03083
    Location:127213
    MtN3_slv; Sugar efflux transporter for intercellular exchange

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    176975744..176978124 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281615.1XP_063137685.1  sugar transporter SWEET1 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZYT4