Srp14 signal recognition particle 14 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Srp14provided by RGD
Official Full Name: signal recognition particle 14provided by RGD
Primary source: RGD:1308506
See related: EnsemblRapid:ENSRNOG00000007512 AllianceGenome:RGD:1308506
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable 7S RNA binding activity and endoplasmic reticulum signal peptide binding activity. Predicted to be involved in protein targeting to ER. Predicted to be located in nucleus. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Orthologous to human SRP14 (signal recognition particle 14). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Heart (RPKM 470.7), Muscle (RPKM 467.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q35

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (125896128..125899819, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (105442184..105445875, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (110245936..110249627, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables 7S RNA binding	IEA Inferred from Electronic Annotation more info
enables endoplasmic reticulum signal peptide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in SRP-dependent cotranslational protein targeting to membrane	IEA Inferred from Electronic Annotation more info
involved_in protein targeting to ER	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein targeting to ER	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of signal recognition particle, endoplasmic reticulum targeting	IBA Inferred from Biological aspect of Ancestor more info
part_of signal recognition particle, endoplasmic reticulum targeting	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: signal recognition particle 14 kDa protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.