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Chchd5 coiled-coil-helix-coiled-coil-helix domain containing 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 296147, updated on 27-Nov-2024

Summary

Official Symbol
Chchd5provided by RGD
Official Full Name
coiled-coil-helix-coiled-coil-helix domain containing 5provided by RGD
Primary source
RGD:1307809
See related
EnsemblRapid:ENSRNOG00000018491 AllianceGenome:RGD:1307809
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in cellular respiration. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial intermembrane space. Orthologous to human CHCHD5 (coiled-coil-helix-coiled-coil-helix domain containing 5). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 86.0), Kidney (RPKM 67.5) and 9 other tissues See more
Orthologs
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Genomic context

See Chchd5 in Genome Data Viewer
Location:
3q36
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (136815034..136819230)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (116361845..116372238)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (121659962..121664286)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene tubulin tyrosine ligase Neighboring gene RNA polymerase I subunit B Neighboring gene uncharacterized LOC134486439 Neighboring gene uncharacterized LOC120101659 Neighboring gene solute carrier family 20 member 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cellular respiration IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in mitochondrial intermembrane space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
coiled-coil-helix-coiled-coil-helix domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106509.1NP_001099979.1  coiled-coil-helix-coiled-coil-helix domain-containing protein 5 isoform 2

    See identical proteins and their annotated locations for NP_001099979.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473949
    UniProtKB/TrEMBL
    A0A8I5ZTB4, A6HQ50
    Conserved Domains (2) summary
    pfam06747
    Location:5892
    CHCH; CHCH domain
    pfam16860
    Location:849
    CX9C; CHCH-CHCH-like Cx9C, IMS import disulfide relay-system,
  2. NM_001430106.1NP_001417035.1  coiled-coil-helix-coiled-coil-helix domain-containing protein 5 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A0A9K3Y7J8, B0BMY5, F7FF20

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    136815034..136819230
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006234969.5XP_006235031.1  coiled-coil-helix-coiled-coil-helix domain-containing protein 5 isoform X2

    Related
    ENSRNOP00000024942.6, ENSRNOT00000024942.8
    Conserved Domains (2) summary
    pfam06747
    Location:5892
    CHCH; CHCH domain
    pfam16860
    Location:849
    CX9C; CHCH-CHCH-like Cx9C, IMS import disulfide relay-system,
  2. XM_039104574.2XP_038960502.1  coiled-coil-helix-coiled-coil-helix domain-containing protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8I6GJ66
    Conserved Domains (2) summary
    pfam06747
    Location:5892
    CHCH; CHCH domain
    pfam16860
    Location:749
    CX9C; CHCH-CHCH-like Cx9C, IMS import disulfide relay-system,