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Pabpc1l poly(A) binding protein, cytoplasmic 1-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 296351, updated on 9-Dec-2024

Summary

Official Symbol
Pabpc1lprovided by RGD
Official Full Name
poly(A) binding protein, cytoplasmic 1-likeprovided by RGD
Primary source
RGD:1563142
See related
EnsemblRapid:ENSRNOG00000012750 AllianceGenome:RGD:1563142
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563142
Summary
Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Predicted to act upstream of or within RNA metabolic process; nucleus localization; and oocyte maturation. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasmic stress granule; cytosol; and nucleus. Orthologous to human PABPC1L (poly(A) binding protein cytoplasmic 1 like). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Spleen (RPKM 5.2), Thymus (RPKM 4.2) and 9 other tissues See more
Orthologs
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Genomic context

See Pabpc1l in Genome Data Viewer
Location:
3q42
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (173111856..173145389)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (152692825..152725997)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (160410733..160447073)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene regulating synaptic membrane exocytosis 4 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta Neighboring gene translocase of outer mitochondrial membrane 34 Neighboring gene serine/threonine kinase 4 Neighboring gene potassium voltage-gated channel, modifier subfamily S, member 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables poly(A) binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables poly(U) RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
polyadenylate-binding protein 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    173111856..173145389
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063285213.1XP_063141283.1  polyadenylate-binding protein 1-like

    UniProtKB/TrEMBL
    D3ZAS7
    Related
    ENSRNOP00000052046.4, ENSRNOT00000055172.5