U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rhno1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 297627, updated on 27-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Rhno1provided by RGD
Official Full Name
RAD9-HUS1-RAD1 interacting nuclear orphan 1provided by RGD
Primary source
RGD:1359404
See related
EnsemblRapid:ENSRNOG00000028517 AllianceGenome:RGD:1359404
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable chromatin-protein adaptor activity. Predicted to be involved in several processes, including DNA repair; cellular response to radiation; and regulation of cell cycle process. Predicted to be active in chromatin; nucleus; and site of double-strand break. Orthologous to human RHNO1 (RAD9-HUS1-RAD1 interacting nuclear orphan 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 82.2), Thymus (RPKM 80.3) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Rhno1 in Genome Data Viewer
Location:
4q42
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (163320141..163325527, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (161634047..161639437, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (161679674..161685060, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene influenza virus NS1A binding protein, pseudogene 1 Neighboring gene TUB like protein 3 Neighboring gene forkhead box M1 Neighboring gene testis expressed 52 Neighboring gene nuclear receptor interacting protein 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Involvement of C12orf32 overexpression in breast carcinogenesis. Kim JW, et al. Int J Oncol, 2010 Oct. PMID 20811708
  2. A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. Cotta-Ramusino C, et al. Science, 2011 Jun 10. PMID 21659603, Free PMC Article
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC94282

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables chromatin-protein adaptor activity ISO
Inferred from Sequence Orthology
more info
  
enables chromatin-protein adaptor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA damage checkpoint signaling ISO
Inferred from Sequence Orthology
more info
  
involved_in cellular response to UV ISO
Inferred from Sequence Orthology
more info
  
involved_in cellular response to ionizing radiation ISO
Inferred from Sequence Orthology
more info
  
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in double-strand break repair via alternative nonhomologous end joining ISO
Inferred from Sequence Orthology
more info
  
involved_in double-strand break repair via alternative nonhomologous end joining ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of G0 to G1 transition ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to site of double-strand break ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to site of double-strand break ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in recombinational repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in recombinational repair ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in chromatin ISO
Inferred from Sequence Orthology
more info
  
is_active_in chromosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chromosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
is_active_in site of double-strand break ISO
Inferred from Sequence Orthology
more info
  
is_active_in site of double-strand break ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001401973.1 → NP_001388902.1  RAD9, HUS1, RAD1-interacting nuclear orphan protein 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004
    UniProtKB/Swiss-Prot
    Q6AY26
    Related
    ENSRNOP00000036772.3, ENSRNOT00000039086.6

  2. NM_001401974.1 → NP_001388903.1  RAD9, HUS1, RAD1-interacting nuclear orphan protein 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004
    UniProtKB/Swiss-Prot
    Q6AY26

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    163320141..163325527 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063285914.1 → XP_063141984.1  RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q6AY26

  2. XM_063285911.1 → XP_063141981.1  RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q6AY26

  3. XM_063285912.1 → XP_063141982.1  RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q6AY26

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001007649.1: Suppressed sequence

    Description
    NM_001007649.1: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6AY26.1 GenPept UniProtKB/Swiss-Prot:Q6AY26

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials