Cibar1 CBY1 interacting BAR domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cibar1provided by RGD
Official Full Name: CBY1 interacting BAR domain containing 1provided by RGD
Primary source: RGD:1310681
See related: EnsemblRapid:ENSRNOG00000016338 AllianceGenome:RGD:1310681
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fam92a; Fam92a1; RGD1310681
Summary: Predicted to enable phospholipid binding activity. Predicted to be involved in several processes, including inner mitochondrial membrane organization; membrane tubulation; and positive regulation of smoothened signaling pathway. Predicted to be located in several cellular components, including centriole; ciliary base; and mitochondrial crista. Predicted to be active in ciliary basal body and ciliary transition zone. Orthologous to human CIBAR1 (CBY1 interacting BAR domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Testes (RPKM 189.1), Brain (RPKM 135.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q13

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (30411325..30429770, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (25613993..25632440, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (25732457..25750953, complement)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables phospholipid binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in inner mitochondrial membrane organization	ISO Inferred from Sequence Orthology more info
involved_in inner mitochondrial membrane organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in limb morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in membrane organization	ISO Inferred from Sequence Orthology more info
involved_in membrane tubulation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of smoothened signaling pathway	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in centriole	ISO Inferred from Sequence Orthology more info
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary basal body	ISO Inferred from Sequence Orthology more info
located_in ciliary base	ISO Inferred from Sequence Orthology more info
is_active_in ciliary transition zone	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary transition zone	ISO Inferred from Sequence Orthology more info
located_in cilium	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrial crista	ISO Inferred from Sequence Orthology more info
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: CBY1 interacting BAR domain containing 1; CBY1-interacting BAR domain-containing protein 1

Names: family with sequence similarity 92 member A; family with sequence similarity 92, member A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001431154.1 → NP_001418083.1 CBY1 interacting BAR domain containing 1 isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000005
NM_001431155.1 → NP_001418084.1 CBY1 interacting BAR domain containing 1 isoform 2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000005
NM_001431156.1 → NP_001418085.1 CBY1 interacting BAR domain containing 1 isoform 3

Status: VALIDATED

Source sequence(s)

JAXUCZ010000005

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086023.1 Reference GRCr8

Range

30411325..30429770 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063261262.1 → XP_063117332.1 CBY1-interacting BAR domain-containing protein 1 isoform X1

Related

ENSRNOP00000084687.2, ENSRNOT00000115551.2
XM_063261263.1 → XP_063117333.1 CBY1-interacting BAR domain-containing protein 1 isoform X2

Related

ENSRNOP00000022249.8, ENSRNOT00000022249.9
XM_063261265.1 → XP_063117335.1 CBY1-interacting BAR domain-containing protein 1 isoform X4
XM_002729463.7 → XP_002729509.2 CBY1-interacting BAR domain-containing protein 1 isoform X6
XM_063261266.1 → XP_063117336.1 CBY1-interacting BAR domain-containing protein 1 isoform X5
XM_063261264.1 → XP_063117334.1 CBY1-interacting BAR domain-containing protein 1 isoform X3
XM_039110944.2 → XP_038966872.1 CBY1-interacting BAR domain-containing protein 1 isoform X7

Conserved Domains (1) summary

cl12013
Location:78 → 156

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature