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Fggy FGGY carbohydrate kinase domain containing [ Rattus norvegicus (Norway rat) ]

Gene ID: 298250, updated on 4-Jan-2025

Summary

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Official Symbol
Fggyprovided by RGD
Official Full Name
FGGY carbohydrate kinase domain containingprovided by RGD
Primary source
RGD:1359429
See related
EnsemblRapid:ENSRNOG00000008907 AllianceGenome:RGD:1359429
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable D-ribulokinase activity. Predicted to be involved in carbohydrate phosphorylation; neuron cellular homeostasis; and pentose metabolic process. Predicted to be active in cytoplasm. Orthologous to human FGGY (FGGY carbohydrate kinase domain containing). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Liver (RPKM 76.7), Kidney (RPKM 62.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fggy in Genome Data Viewer
Location:
5q33
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (115514573..115901713)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (110398866..110786019)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (114516860..114901571)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120102924 Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC103692418 Neighboring gene uncharacterized LOC120102925 Neighboring gene hook microtubule-tethering protein 1 Neighboring gene cytochrome P450 2J3-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Whole-genome analysis of sporadic amyotrophic lateral sclerosis. Dunckley T, et al. N Engl J Med, 2007 Aug 23. PMID 17671248
  2. Molecular Identification of d-Ribulokinase in Budding Yeast and Mammals. Singh C, et al. J Biol Chem, 2017 Jan 20. PMID 27909055, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC94804

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables D-ribulokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in carbohydrate phosphorylation ISO
Inferred from Sequence Orthology
more info
  
involved_in neuron cellular homeostasis ISO
Inferred from Sequence Orthology
more info
  
involved_in pentose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
FGGY carbohydrate kinase domain-containing protein
NP_001013954.2
XP_006238472.1
XP_017448749.1
XP_017448750.1
XP_038965461.1
XP_038965462.2
XP_038965464.1
XP_063143446.1
XP_063143447.1
XP_063143448.1
XP_063143449.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013932.2 → NP_001013954.2  FGGY carbohydrate kinase domain-containing protein

    See identical proteins and their annotated locations for NP_001013954.2

    Status: VALIDATED

    Source sequence(s)
    BC090077, CB316436
    UniProtKB/TrEMBL
    F1LSP9
    Conserved Domains (1) summary
    cd07782
    Location:11 → 545
    FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    115514573..115901713
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017593260.3 → XP_017448749.1  FGGY carbohydrate kinase domain-containing protein isoform X1

    UniProtKB/TrEMBL
    F1LSP9
    Related
    ENSRNOP00000011767.6, ENSRNOT00000011767.7
    Conserved Domains (1) summary
    cd07782
    Location:11 → 545
    FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

  2. XM_017593261.3 → XP_017448750.1  FGGY carbohydrate kinase domain-containing protein isoform X1

    UniProtKB/TrEMBL
    F1LSP9
    Conserved Domains (1) summary
    cd07782
    Location:11 → 545
    FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

  3. XM_063287376.1 → XP_063143446.1  FGGY carbohydrate kinase domain-containing protein isoform X3

    UniProtKB/TrEMBL
    F1LSP9
    Related
    ENSRNOP00000109575.1, ENSRNOT00000145188.1

  4. XM_039109534.2 → XP_038965462.2  FGGY carbohydrate kinase domain-containing protein isoform X2

    UniProtKB/TrEMBL
    A0A8I6AN02

  5. XM_039109533.2 → XP_038965461.1  FGGY carbohydrate kinase domain-containing protein isoform X1

    UniProtKB/TrEMBL
    F1LSP9
    Related
    ENSRNOP00000098720.1, ENSRNOT00000126021.1
    Conserved Domains (1) summary
    cd07782
    Location:11 → 545
    FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

  6. XM_006238410.5 → XP_006238472.1  FGGY carbohydrate kinase domain-containing protein isoform X1

    See identical proteins and their annotated locations for XP_006238472.1

    UniProtKB/TrEMBL
    F1LSP9
    Conserved Domains (1) summary
    cd07782
    Location:11 → 545
    FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

  7. XM_039109536.2 → XP_038965464.1  FGGY carbohydrate kinase domain-containing protein isoform X5

    UniProtKB/TrEMBL
    A6JRI3
    Conserved Domains (1) summary
    cl17037
    Location:2 → 336
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  8. XM_063287379.1 → XP_063143449.1  FGGY carbohydrate kinase domain-containing protein isoform X6

  9. XM_063287378.1 → XP_063143448.1  FGGY carbohydrate kinase domain-containing protein isoform X5

    UniProtKB/TrEMBL
    A6JRI3

  10. XM_063287377.1 → XP_063143447.1  FGGY carbohydrate kinase domain-containing protein isoform X4

RNA

  1. XR_010066354.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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