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Raver1 ribonucleoprotein, PTB-binding 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298705, updated on 4-Jan-2025

Summary

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Official Symbol
Raver1provided by RGD
Official Full Name
ribonucleoprotein, PTB-binding 1provided by RGD
Primary source
RGD:1359190
See related
EnsemblRapid:ENSRNOG00000020710 AllianceGenome:RGD:1359190
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Raver1h
Summary
Predicted to enable RNA binding activity. Predicted to be located in cytoplasm and nucleus. Orthologous to human RAVER1 (ribonucleoprotein, PTB binding 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 109.3), Spleen (RPKM 87.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Raver1 in Genome Data Viewer
Location:
8q13
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (27886641..27907192, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (19610464..19629188, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (22092084..22111863, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene zinc finger, GATA-like protein 1 Neighboring gene ferredoxin 2 Neighboring gene tyrosine kinase 2 Neighboring gene uncharacterized LOC108351660

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing. Gromak N, et al. EMBO J, 2003 Dec 1. PMID 14633994, Free PMC Article
  2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribonucleoprotein PTB-binding 1
Names
RAVER1 homolog
protein raver-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013939.1 → NP_001013961.1  ribonucleoprotein PTB-binding 1

    See identical proteins and their annotated locations for NP_001013961.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083865
    UniProtKB/Swiss-Prot
    Q5XI28
    UniProtKB/TrEMBL
    A6JNN8
    Related
    ENSRNOP00000048510.3, ENSRNOT00000046983.5
    Conserved Domains (3) summary
    cd12663
    Location:59 → 129
    RRM1_RAVER1; RNA recognition motif 1 in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cd12667
    Location:219 → 306
    RRM3_RAVER1; RNA recognition motif 3 in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cl17169
    Location:133 → 209
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    27886641..27907192 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039080982.2 → XP_038936910.1  ribonucleoprotein PTB-binding 1 isoform X3

  2. XM_063265041.1 → XP_063121111.1  ribonucleoprotein PTB-binding 1 isoform X2

  3. XM_063265040.1 → XP_063121110.1  ribonucleoprotein PTB-binding 1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XI28.1 GenPept UniProtKB/Swiss-Prot:Q5XI28

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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