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Clip4 CAP-GLY domain containing linker protein family, member 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298801, updated on 9-Dec-2024

Summary

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Symbol
Clip4provided by RGD
Full Name
CAP-GLY domain containing linker protein family, member 4provided by RGD
Primary source
RGD:1311049
See related
EnsemblRapid:ENSRNOG00000008806 AllianceGenome:RGD:1311049
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rsnl2; RGD1311049
Summary
Predicted to be located in intracellular membrane-bounded organelle. Orthologous to human CLIP4 (CAP-Gly domain containing linker protein family member 4). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Testes (RPKM 542.2), Muscle (RPKM 310.9) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Clip4 in Genome Data Viewer
Location:
6q14
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (29359628..29449365, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (23616280..23697625, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (23222020..23316962, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351183 Neighboring gene ALK receptor tyrosine kinase Neighboring gene stratifin like 1 Neighboring gene uncharacterized LOC108351180 Neighboring gene histidine-rich glycoprotein-like Neighboring gene TOG array regulator of axonemal microtubules 2 Neighboring gene photoreceptor cilium actin regulator

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
CAP-Gly domain-containing linker protein 4
Names
restin-like 2
restin-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013942.2 → NP_001013964.1  CAP-Gly domain-containing linker protein 4 isoform 2

    See identical proteins and their annotated locations for NP_001013964.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/Swiss-Prot
    Q66HD5
    UniProtKB/TrEMBL
    A0A0G2K6G4
    Related
    ENSRNOP00000073802.3, ENSRNOT00000085708.3
    Conserved Domains (4) summary
    cd00204
    Location:98 → 252
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01302
    Location:488 → 551
    CAP_GLY; CAP-Gly domain
    pfam12796
    Location:111 → 217
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:153 → 184
    ANK; ANK repeat [structural motif]

  2. NM_001428603.1 → NP_001415532.1  CAP-Gly domain-containing linker protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  3. NM_001428604.1 → NP_001415533.1  CAP-Gly domain-containing linker protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  4. NM_001428605.1 → NP_001415534.1  CAP-Gly domain-containing linker protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  5. NM_001428606.1 → NP_001415535.1  CAP-Gly domain-containing linker protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  6. NM_001428607.1 → NP_001415536.1  CAP-Gly domain-containing linker protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  7. NM_001428608.1 → NP_001415537.1  CAP-Gly domain-containing linker protein 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/Swiss-Prot
    Q66HD5
    UniProtKB/TrEMBL
    A0A0G2K6G4

  8. NM_001428609.1 → NP_001415538.1  CAP-Gly domain-containing linker protein 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/Swiss-Prot
    Q66HD5
    UniProtKB/TrEMBL
    A0A0G2K6G4

  9. NM_001428610.1 → NP_001415539.1  CAP-Gly domain-containing linker protein 4 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

RNA

  1. NR_190422.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  2. NR_190423.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  3. NR_190424.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  4. NR_190425.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  5. NR_190426.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    29359628..29449365 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

  2. NC_086024.1 Reference GRCr8

    Range
    29349245..29351890 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063261626.1 → XP_063117696.1  CAP-Gly domain-containing linker protein 4 isoform X1

    Related
    ENSRNOP00000111998.1, ENSRNOT00000144084.1

  2. XM_063261628.1 → XP_063117698.1  CAP-Gly domain-containing linker protein 4 isoform X1

  3. XM_063261627.1 → XP_063117697.1  CAP-Gly domain-containing linker protein 4 isoform X1

RNA

  1. XR_010052058.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q66HD5.1 GenPept UniProtKB/Swiss-Prot:Q66HD5

Gene LinkOut

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