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Mrpl13 mitochondrial ribosomal protein L13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299938, updated on 4-Jan-2025

Summary

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Official Symbol
Mrpl13provided by RGD
Official Full Name
mitochondrial ribosomal protein L13provided by RGD
Primary source
RGD:1359587
See related
EnsemblRapid:ENSRNOG00000004401 AllianceGenome:RGD:1359587
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in negative regulation of translation. Predicted to be located in mitochondrial ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in ribosome. Orthologous to human MRPL13 (mitochondrial ribosomal protein L13). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Heart (RPKM 503.7), Muscle (RPKM 269.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mrpl13 in Genome Data Viewer
Location:
7q32
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (88841265..88862821, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (86951541..86973147, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (95288400..95309997, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L31, pseudogene 5 Neighboring gene collagen type XIV alpha 1 chain Neighboring gene eukaryotic translation initiation factor 1, pseudogene 1 Neighboring gene uncharacterized LOC120093658 Neighboring gene MDM2 binding protein Neighboring gene syntrophin, beta 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome. Cámara Y, et al. Cell Metab, 2011 May 4. PMID 21531335
  2. Properties of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L and its interactions with mammalian mitochondrial ribosomes. Haque ME, et al. J Biol Chem, 2010 Sep 3. PMID 20601428, Free PMC Article
  3. Initial steps in RNA processing and ribosome assembly occur at mitochondrial DNA nucleoids. Bogenhagen DF, et al. Cell Metab, 2014 Apr 1. PMID 24703694
  4. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. Kenmochi N, et al. Genomics, 2001 Sep. PMID 11543634
  5. Structures of the human mitochondrial ribosome in native states of assembly. Brown A, et al. Nat Struct Mol Biol, 2017 Oct. PMID 28892042, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC105961

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrial ribosome ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
is_active_in ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein uL13m
Names
39S ribosomal protein L13, mitochondrial
NP_001006986.1
XP_006241713.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006985.1 → NP_001006986.1  large ribosomal subunit protein uL13m

    See identical proteins and their annotated locations for NP_001006986.1

    Status: PROVISIONAL

    Source sequence(s)
    BC084710
    UniProtKB/TrEMBL
    F7FDQ1, Q5XFW4
    Conserved Domains (1) summary
    pfam00572
    Location:17 → 140
    Ribosomal_L13; Ribosomal protein L13

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    88841265..88862821 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006241651.3 → XP_006241713.1  large ribosomal subunit protein uL13m isoform X1

    See identical proteins and their annotated locations for XP_006241713.1

    UniProtKB/TrEMBL
    A6HRH4
    Related
    ENSRNOP00000005815.4, ENSRNOT00000005815.8
    Conserved Domains (1) summary
    pfam00572
    Location:1 → 124
    Ribosomal_L13; Ribosomal protein L13
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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