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Fam227a family with sequence similarity 227, member A [ Rattus norvegicus (Norway rat) ]

Gene ID: 300074, updated on 27-Nov-2024

Summary

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Official Symbol
Fam227aprovided by RGD
Official Full Name
family with sequence similarity 227, member Aprovided by RGD
Primary source
RGD:1305939
See related
EnsemblRapid:ENSRNOG00000021795 AllianceGenome:RGD:1305939
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305939
Summary
Orthologous to human FAM227A (family with sequence similarity 227 member A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 46.6), Testes (RPKM 36.4) and 4 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fam227a in Genome Data Viewer
Location:
7q34
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (113054751..113096898, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (111174362..111216513, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (120846166..120891738, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene DEAD-box helicase 17 Neighboring gene DNA meiotic recombinase 1 Neighboring gene uncharacterized LOC134479938 Neighboring gene chibby 1, beta catenin antagonist Neighboring gene translocase of outer mitochondrial membrane 22

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
protein FAM227A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130581.3 → NP_001124053.2  protein FAM227A

    See identical proteins and their annotated locations for NP_001124053.2

    Status: VALIDATED

    Source sequence(s)
    BC097470, JAXUCZ010000007
    UniProtKB/TrEMBL
    F1LMV2
    Related
    ENSRNOP00000053025.5, ENSRNOT00000056179.7
    Conserved Domains (1) summary
    pfam14922
    Location:136 → 297
    FWWh; Protein of unknown function

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    113054751..113096898 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039078836.1 → XP_038934764.1  protein FAM227A isoform X1

    Conserved Domains (1) summary
    pfam14922
    Location:147 → 297
    FWWh; Protein of unknown function

  2. XM_039078837.1 → XP_038934765.1  protein FAM227A isoform X2

    UniProtKB/TrEMBL
    A0A0G2JTT0, Q4V8A5
    Related
    ENSRNOP00000068832.2, ENSRNOT00000078320.3
    Conserved Domains (1) summary
    pfam14922
    Location:147 → 297
    FWWh; Protein of unknown function

RNA

  1. XR_005486589.2 RNA Sequence

  2. XR_010052960.1 RNA Sequence

  3. XR_005486591.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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