Dnal4 dynein, axonemal, light chain 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Dnal4provided by RGD
Official Full Name: dynein, axonemal, light chain 4provided by RGD
Primary source: RGD:1309099
See related: EnsemblRapid:ENSRNOG00000015583 AllianceGenome:RGD:1309099
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Dnalc4
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in microtubule-based process. Predicted to be located in cytoplasm and microtubule. Predicted to be part of dynein complex. Human ortholog(s) of this gene implicated in congenital mirror movement disorder. Orthologous to human DNAL4 (dynein axonemal light chain 4). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Kidney (RPKM 92.2), Lung (RPKM 83.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q34

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (113192807..113205665, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (111312424..111325283, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (120987438..121000272, complement)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH141025 (e-PCR)
- UniSTS:223025

AB010031 (e-PCR)
- UniSTS:160471

RH127229 (e-PCR)
- UniSTS:167159

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in microtubule-based process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of dynein complex	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dynein axonemal light chain 4

Names: dynein light chain 4, axonemal

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.