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Trabd TraB domain containing [ Rattus norvegicus (Norway rat) ]

Gene ID: 300142, updated on 4-Jan-2025

Summary

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Official Symbol
Trabdprovided by RGD
Official Full Name
TraB domain containingprovided by RGD
Primary source
RGD:1310875
See related
EnsemblRapid:ENSRNOG00000029095 AllianceGenome:RGD:1310875
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310875
Summary
Predicted to enable mitochondrion-mitochondrion outer membrane tether activity. Predicted to be involved in mitochondrial fusion. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial outer membrane. Orthologous to human TRABD (TraB domain containing). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Heart (RPKM 127.8), Kidney (RPKM 105.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Trabd in Genome Data Viewer
Location:
7q34
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (122034685..122045657)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (120155042..120166015)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (130058252..130069224)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene Mov10 like RNA helicase 1 Neighboring gene uncharacterized LOC120093824 Neighboring gene pannexin 2 Neighboring gene selenoprotein O Neighboring gene tubulin gamma complex component 6 Neighboring gene histone deacetylase 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. p38α MAPK proximity assay reveals a regulatory mechanism of alternative splicing in cardiomyocytes. Dumont AA, et al. Biochim Biophys Acta Mol Cell Res, 2019 Dec. PMID 31505169
  2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables mitochondrion-mitochondrion outer membrane tether activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in mitochondrial fusion IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial fusion ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
traB domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106788.1 → NP_001100258.1  traB domain-containing protein

    See identical proteins and their annotated locations for NP_001100258.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474027
    UniProtKB/TrEMBL
    A6K7I9, D3ZML4
    Related
    ENSRNOP00000039102.3, ENSRNOT00000052087.5
    Conserved Domains (1) summary
    cl12050
    Location:72 → 274
    TraB; TraB family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    122034685..122045657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242183.4 → XP_006242245.1  traB domain-containing protein isoform X2

    See identical proteins and their annotated locations for XP_006242245.1

    UniProtKB/TrEMBL
    A6K7I9, D3ZML4
    Conserved Domains (1) summary
    cl12050
    Location:72 → 274
    TraB; TraB family

  2. XM_063263332.1 → XP_063119402.1  traB domain-containing protein isoform X1

    Related
    ENSRNOP00000112123.1, ENSRNOT00000131073.1

  3. XM_039078855.2 → XP_038934783.1  traB domain-containing protein isoform X3

    Conserved Domains (1) summary
    cd14726
    Location:27 → 225
    TraB_PrgY-like; TraB/PryY confer plasmid-borne pheromone resistance
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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