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Srbd1 S1 RNA binding domain 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 301665, updated on 27-Nov-2024

Summary

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Official Symbol
Srbd1provided by RGD
Official Full Name
S1 RNA binding domain 1provided by RGD
Primary source
RGD:1562788
See related
EnsemblRapid:ENSRNOG00000014720 AllianceGenome:RGD:1562788
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562788
Summary
Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Orthologous to human SRBD1 (S1 RNA binding domain 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 153.9), Spleen (RPKM 119.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Srbd1 in Genome Data Viewer
Location:
6q12
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (14226551..14417494)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (8473591..8664544)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (9266559..9459212, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120093190 Neighboring gene uncharacterized LOC102551445 Neighboring gene uncharacterized LOC102551210 Neighboring gene uncharacterized LOC120103470

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in nucleobase-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
S1 RNA-binding domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399769.1 → NP_001386698.1  S1 RNA-binding domain-containing protein 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    14226551..14417494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039113056.2 → XP_038968984.1  S1 RNA-binding domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I6GLE9
    Related
    ENSRNOP00000102267.1, ENSRNOT00000144704.1
    Conserved Domains (1) summary
    COG2183
    Location:203 → 977
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]

  2. XM_006239708.4 → XP_006239770.1  S1 RNA-binding domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006239770.1

    UniProtKB/TrEMBL
    A0A8I6GLE9, D4A9B0
    Related
    ENSRNOP00000019895.7, ENSRNOT00000019894.9
    Conserved Domains (5) summary
    COG2183
    Location:206 → 980
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]
    cd05685
    Location:907 → 978
    S1_Tex; S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression. ...
    pfam09371
    Location:215 → 410
    Tex_N; Tex-like protein N-terminal domain
    pfam12836
    Location:701 → 763
    HHH_3; Helix-hairpin-helix motif
    pfam16921
    Location:534 → 659
    Tex_YqgF; Tex protein YqgF-like domain

  3. XM_039113059.2 → XP_038968987.1  S1 RNA-binding domain-containing protein 1 isoform X5

    Conserved Domains (1) summary
    COG2183
    Location:206 → 620
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]

  4. XM_039113057.2 → XP_038968985.1  S1 RNA-binding domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A6H9G1
    Conserved Domains (1) summary
    COG2183
    Location:206 → 824
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]

  5. XM_039113058.1 → XP_038968986.1  S1 RNA-binding domain-containing protein 1 isoform X4

    Conserved Domains (1) summary
    COG2183
    Location:6 → 668
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]
Nucleotide Protein Strain
Heading Accession and Version

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