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Pgap6 post-GPI attachment to proteins 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303004, updated on 27-Nov-2024

Summary

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Official Symbol
Pgap6provided by RGD
Official Full Name
post-GPI attachment to proteins 6provided by RGD
Primary source
RGD:1311395
See related
EnsemblRapid:ENSRNOG00000020374 AllianceGenome:RGD:1311395
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
M83; Tmem8; Tmem8a
Summary
Predicted to be located in plasma membrane. Orthologous to human PGAP6 (post-GPI attachment to proteins 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 169.3), Testes (RPKM 28.1) and 6 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Pgap6 in Genome Data Viewer
Location:
10q12
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15643081..15652912)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (15138918..15148431)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15484952..15495380)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L34-like Neighboring gene NME/NM23 nucleoside diphosphate kinase 4 Neighboring gene mitochondrial ribosomal protein L28 Neighboring gene axin 1 Neighboring gene U6atac minor spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Integral and associated lysosomal membrane proteins. Schröder B, et al. Traffic, 2007 Dec. PMID 17897319
  2. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Principe S, et al. Proteomics, 2013 May. PMID 23533145, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
post-GPI attachment to proteins factor 6
Names
post-glycosylphosphatidylinositol attachment to proteins 6
transmembrane protein 8 (five membrane-spanning domains)
transmembrane protein 8A
type I transmembrane protein
NP_001100461.1
XP_063125016.1
XP_063125017.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106991.1 → NP_001100461.1  post-GPI attachment to proteins factor 6 precursor

    See identical proteins and their annotated locations for NP_001100461.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    A0A0G2JV00, A6HD88, D3ZKI8
    Related
    ENSRNOP00000027609.4, ENSRNOT00000027609.7
    Conserved Domains (1) summary
    pfam12036
    Location:553 → 728
    DUF3522; Protein of unknown function (DUF3522)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    15643081..15652912
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063268946.1 → XP_063125016.1  post-GPI attachment to proteins factor 6 isoform X1

    Related
    ENSRNOP00000082896.2, ENSRNOT00000110211.2

  2. XM_063268947.1 → XP_063125017.1  post-GPI attachment to proteins factor 6 isoform X2

RNA

  1. XR_010055170.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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