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Hs3st3b1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303218, updated on 27-Nov-2024

Summary

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Official Symbol
Hs3st3b1provided by RGD
Official Full Name
heparan sulfate-glucosamine 3-sulfotransferase 3B1provided by RGD
Primary source
RGD:1307326
See related
EnsemblRapid:ENSRNOG00000003384 AllianceGenome:RGD:1307326
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hs3st3b
Summary
Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Predicted to be involved in branching involved in ureteric bud morphogenesis; glycosaminoglycan biosynthetic process; and heparan sulfate proteoglycan biosynthetic process. Predicted to act upstream of or within protein sulfation. Predicted to be located in plasma membrane. Orthologous to human HS3ST3B1 (heparan sulfate-glucosamine 3-sulfotransferase 3B1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 69.7), Spleen (RPKM 32.8) and 6 other tissues See more
Orthologs
human all
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Genomic context

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See Hs3st3b1 in Genome Data Viewer
Location:
10q23
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (49060693..49093185, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (48561473..48593970, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (50369097..50402584, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC120095117 Neighboring gene cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 Neighboring gene uncharacterized LOC120095119 Neighboring gene uncharacterized LOC120095118

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry. Shukla D, et al. Cell, 1999 Oct 1. PMID 10520990
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in branching involved in ureteric bud morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in glycosaminoglycan biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in heparan sulfate proteoglycan biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within protein sulfation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
heparan sulfate glucosamine 3-O-sulfotransferase 3B1
Names
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
NP_001178575.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191646.1 → NP_001178575.1  heparan sulfate glucosamine 3-O-sulfotransferase 3B1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    D3ZTA9
    Related
    ENSRNOP00000004546.3, ENSRNOT00000004546.8
    Conserved Domains (1) summary
    pfam00685
    Location:137 → 374
    Sulfotransfer_1; Sulfotransferase domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    49060693..49093185 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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