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lpla - lipoprotein lipase a

Predicted to enable apolipoprotein binding activity; lipoprotein lipase activity; and phospholipase A1 activity. Acts upstream of or within definitive hemopoiesis and response to (R)-carnitine. Predicted to be located in extracellular region and plasma membrane. Predicted to be part of chylomicron and very-low-density lipoprotein particle. Predicted to be active in extracellular space. Is expressed in several structures, including digestive system; head; immature eye; midbrain; and ovary. Human ortholog(s) of this gene implicated in Alzheimer's disease; artery disease (multiple); familial hyperlipidemia (multiple); muscular disease; and type 2 diabetes mellitus. Orthologous to human LPL (lipoprotein lipase). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa