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Slc38a10 solute carrier family 38, member 10 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303740, updated on 27-Nov-2024

Summary

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Official Symbol
Slc38a10provided by RGD
Official Full Name
solute carrier family 38, member 10provided by RGD
Primary source
RGD:1306356
See related
EnsemblRapid:ENSRNOG00000004604 AllianceGenome:RGD:1306356
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306356
Summary
Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to act upstream of or within bone development. Predicted to be located in Golgi apparatus. Predicted to be active in membrane. Orthologous to human SLC38A10 (solute carrier family 38 member 10). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 166.5), Lung (RPKM 163.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Slc38a10 in Genome Data Viewer
Location:
10q32.3
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (105885250..105935043, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (105386836..105436636, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (109284054..109333907, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene TEPSIN, adaptor related protein complex 4 accessory protein Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 8 Neighboring gene uncharacterized LOC100912167 Neighboring gene BAH domain and coiled-coil containing 1 Neighboring gene uncharacterized LOC120095309

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. SLC38A10 (SNAT10) is Located in ER and Golgi Compartments and Has a Role in Regulating Nascent Protein Synthesis. Tripathi R, et al. Int J Mol Sci, 2019 Dec 12. PMID 31842320, Free PMC Article
  2. Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength. Bassett JH, et al. PLoS Genet, 2012. PMID 22876197, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables active monoatomic ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables inorganic cation transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables monoatomic cation transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables neutral L-amino acid transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables secondary active transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in bone development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within bone development ISO
Inferred from Sequence Orthology
more info
  
involved_in inorganic cation transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic cation transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in neutral amino acid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
solute carrier family 38 member 10
Names
amino acid transporter SLC38A10
putative sodium-coupled neutral amino acid transporter 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001376915.1 → NP_001363844.1  solute carrier family 38 member 10

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A8I5ZRR0, A0A8L2Q2J1
    Related
    ENSRNOP00000006225.7, ENSRNOT00000006225.10
    Conserved Domains (2) summary
    PTZ00121
    Location:396 → 1076
    PTZ00121; MAEBL; Provisional
    cl00456
    Location:6 → 381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    105885250..105935043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_221195.10 → XP_221195.5  solute carrier family 38 member 10 isoform X5

    See identical proteins and their annotated locations for XP_221195.5

    UniProtKB/Swiss-Prot
    E9PT23
    UniProtKB/TrEMBL
    A0A8I5ZRR0
    Conserved Domains (2) summary
    COG0814
    Location:3 → 398
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:6 → 381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  2. XM_063269250.1 → XP_063125320.1  solute carrier family 38 member 10 isoform X12

    Related
    ENSRNOP00000081337.2, ENSRNOT00000095802.2

  3. XM_039086218.2 → XP_038942146.1  solute carrier family 38 member 10 isoform X11

    UniProtKB/TrEMBL
    A0A8I5ZRR0
    Conserved Domains (2) summary
    PTZ00121
    Location:335 → 1016
    PTZ00121; MAEBL; Provisional
    cl00456
    Location:6 → 320
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  4. XM_039086217.2 → XP_038942145.1  solute carrier family 38 member 10 isoform X10

    UniProtKB/TrEMBL
    A6HLB3
    Conserved Domains (2) summary
    PTZ00121
    Location:335 → 1024
    PTZ00121; MAEBL; Provisional
    cl00456
    Location:6 → 320
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  5. XM_063269248.1 → XP_063125318.1  solute carrier family 38 member 10 isoform X7

  6. XM_006247946.4 → XP_006248008.1  solute carrier family 38 member 10 isoform X6

    See identical proteins and their annotated locations for XP_006248008.1

    UniProtKB/TrEMBL
    A0A8I5ZRR0
    Conserved Domains (2) summary
    COG0814
    Location:3 → 398
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:6 → 381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  7. XM_039086215.2 → XP_038942143.1  solute carrier family 38 member 10 isoform X4

    UniProtKB/TrEMBL
    A6HLB3
    Conserved Domains (2) summary
    PTZ00121
    Location:396 → 1028
    PTZ00121; MAEBL; Provisional
    cl00456
    Location:6 → 381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  8. XM_006247943.4 → XP_006248005.1  solute carrier family 38 member 10 isoform X2

    See identical proteins and their annotated locations for XP_006248005.1

    UniProtKB/TrEMBL
    A6HLB3
    Conserved Domains (2) summary
    COG0814
    Location:3 → 398
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:6 → 381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  9. XM_006247944.5 → XP_006248006.1  solute carrier family 38 member 10 isoform X3

    See identical proteins and their annotated locations for XP_006248006.1

    UniProtKB/TrEMBL
    A0A8I6A7H4, A6HLB3
    Related
    ENSRNOP00000086955.1, ENSRNOT00000094909.2
    Conserved Domains (2) summary
    COG0814
    Location:3 → 398
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:6 → 381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  10. XM_002727846.6 → XP_002727892.2  solute carrier family 38 member 10 isoform X1

    See identical proteins and their annotated locations for XP_002727892.2

    UniProtKB/TrEMBL
    A6HLB3
    Conserved Domains (2) summary
    COG0814
    Location:3 → 398
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:6 → 381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  11. XM_063269249.1 → XP_063125319.1  solute carrier family 38 member 10 isoform X9

  12. XM_039086216.2 → XP_038942144.1  solute carrier family 38 member 10 isoform X8

    UniProtKB/TrEMBL
    A6HLB3
    Conserved Domains (2) summary
    PTZ00121
    Location:348 → 1037
    PTZ00121; MAEBL; Provisional
    cl00456
    Location:17 → 333
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  13. XM_039086219.2 → XP_038942147.1  solute carrier family 38 member 10 isoform X13

    UniProtKB/TrEMBL
    A6HLB3
    Conserved Domains (2) summary
    PTZ00121
    Location:251 → 940
    PTZ00121; MAEBL; Provisional
    cl00456
    Location:2 → 236
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  14. XM_039086220.2 → XP_038942148.1  solute carrier family 38 member 10 isoform X14

    Conserved Domains (2) summary
    PTZ00121
    Location:146 → 508
    PTZ00121; MAEBL; Provisional
    cl00456
    Location:2 → 110
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E9PT23.2 GenPept UniProtKB/Swiss-Prot:E9PT23

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