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Zfp184 zinc finger protein 184 [ Rattus norvegicus (Norway rat) ]

Gene ID: 306966, updated on 27-Nov-2024

Summary

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Official Symbol
Zfp184provided by RGD
Official Full Name
zinc finger protein 184provided by RGD
Primary source
RGD:1304798
See related
EnsemblRapid:ENSRNOG00000061612 AllianceGenome:RGD:1304798
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Znf184
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ZNF184 (zinc finger protein 184). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 35.3), Thymus (RPKM 33.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp184 in Genome Data Viewer
Location:
17p11
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (47262566..47299675, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (42588140..42603905, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (44625795..44645549, complement)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene POM121 transmembrane nucleoporin-like 2 Neighboring gene transfer RNA methionine (anticodon CAU) 7 Neighboring gene Tu translation elongation factor, mitochondrial, pseudogene 3 Neighboring gene transfer RNA serine (anticodon AGA) 7 Neighboring gene uncharacterized LOC102555506 Neighboring gene transfer RNA serine (anticodon AGA) 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 184
Names
zinc finger protein 184 (Kruppel-like)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427199.1 → NP_001414128.1  zinc finger protein 184

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A0A8I6AS09, A6KNA5
    Related
    ENSRNOP00000069240.3, ENSRNOT00000077628.3

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    47262566..47299675 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063276446.1 → XP_063132516.1  zinc finger protein 184 isoform X5

    UniProtKB/TrEMBL
    F1M7P0

  2. XM_039096163.2 → XP_038952091.1  zinc finger protein 184 isoform X1

    UniProtKB/TrEMBL
    A0A8I6AS09, A6KNA5
    Conserved Domains (3) summary
    smart00349
    Location:28 → 88
    KRAB; krueppel associated box
    COG5048
    Location:203 → 635
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:288 → 308
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_063276444.1 → XP_063132514.1  zinc finger protein 184 isoform X3

    UniProtKB/TrEMBL
    A0A0G2JUV0
    Related
    ENSRNOP00000097886.2, ENSRNOT00000099295.2

  4. XM_063276443.1 → XP_063132513.1  zinc finger protein 184 isoform X2

  5. XM_063276445.1 → XP_063132515.1  zinc finger protein 184 isoform X3

    UniProtKB/TrEMBL
    A0A0G2JUV0

  6. XM_003751710.6 → XP_003751758.1  zinc finger protein 184 isoform X1

    See identical proteins and their annotated locations for XP_003751758.1

    UniProtKB/TrEMBL
    A0A8I6AS09, A6KNA5
    Conserved Domains (3) summary
    smart00349
    Location:28 → 88
    KRAB; krueppel associated box
    COG5048
    Location:203 → 635
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:288 → 308
    ZF_C2H2; C2H2 Zn finger [structural motif]

  7. XM_039096165.2 → XP_038952093.1  zinc finger protein 184 isoform X3

    UniProtKB/TrEMBL
    A0A0G2JUV0
    Conserved Domains (4) summary
    COG5048
    Location:252 → 660
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:122 → 272
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:256 → 276
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:27 → 68
    KRAB; KRAB box

  8. XM_039096164.2 → XP_038952092.1  zinc finger protein 184 isoform X2

    Conserved Domains (3) summary
    smart00349
    Location:28 → 75
    KRAB; krueppel associated box
    COG5048
    Location:190 → 622
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:275 → 295
    ZF_C2H2; C2H2 Zn finger [structural motif]

  9. XM_006254113.5 → XP_006254175.1  zinc finger protein 184 isoform X1

    See identical proteins and their annotated locations for XP_006254175.1

    UniProtKB/TrEMBL
    A0A8I6AS09, A6KNA5
    Conserved Domains (3) summary
    smart00349
    Location:28 → 88
    KRAB; krueppel associated box
    COG5048
    Location:203 → 635
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:288 → 308
    ZF_C2H2; C2H2 Zn finger [structural motif]

  10. XM_006254118.5 → XP_006254180.1  zinc finger protein 184 isoform X4

    See identical proteins and their annotated locations for XP_006254180.1

    UniProtKB/TrEMBL
    A0A0G2JUV0
    Conserved Domains (3) summary
    COG5048
    Location:209 → 617
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:79 → 229
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:213 → 233
    ZF_C2H2; C2H2 Zn finger [structural motif]

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001100573.1: Suppressed sequence

    Description
    NM_001100573.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from cow: ZNF184 (GeneID:515674).
Nucleotide Protein Strain
Heading Accession and Version

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