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Epb41l4a erythrocyte membrane protein band 4.1 like 4A [ Rattus norvegicus (Norway rat) ]

Gene ID: 307514, updated on 14-Nov-2024

Summary

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Official Symbol
Epb41l4aprovided by RGD
Official Full Name
erythrocyte membrane protein band 4.1 like 4Aprovided by RGD
Primary source
RGD:1306034
See related
EnsemblRapid:ENSRNOG00000026050 AllianceGenome:RGD:1306034
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Epb4.1l4a
Summary
Predicted to enable cytoskeletal protein binding activity. Predicted to be located in cytoskeleton. Orthologous to human EPB41L4A (erythrocyte membrane protein band 4.1 like 4A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 47.9), Lung (RPKM 35.2) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Epb41l4a in Genome Data Viewer
Location:
18p12
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (25680169..25890998, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (25405461..25615392, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (26570051..26788586, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC120098269 Neighboring gene small nucleolar RNA SNORA13 Neighboring gene U7 small nuclear RNA Neighboring gene 60S ribosomal protein L23a-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cytoskeletal protein binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in actomyosin structure organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
band 4.1-like protein 4A
Names
erythrocyte protein band 4.1-like 4a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107397.2 → NP_001100867.1  band 4.1-like protein 4A

    See identical proteins and their annotated locations for NP_001100867.1

    Status: PROVISIONAL

    Source sequence(s)
    BC168858
    UniProtKB/TrEMBL
    B5DEZ0, F1LQE5
    Conserved Domains (3) summary
    cd13186
    Location:23 → 112
    FERM_C_NBL4_NBL5; FERM domain C-lobe of Novel band 4.1-like protein 4 and 5 (NBL4 and 5)
    pfam08736
    Location:127 → 171
    FA; FERM adjacent (FA)
    cl09511
    Location:2 → 27
    FERM_B-lobe; FERM domain B-lobe

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    25680169..25890998 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063277376.1 → XP_063133446.1  band 4.1-like protein 4A isoform X2

    Related
    ENSRNOP00000104301.1, ENSRNOT00000142918.1

  2. XM_006254584.5 → XP_006254646.1  band 4.1-like protein 4A isoform X1

    See identical proteins and their annotated locations for XP_006254646.1

    UniProtKB/TrEMBL
    A0A0G2JW20, A0A8I6ATD3
    Conserved Domains (5) summary
    smart00295
    Location:13 → 211
    B41; Band 4.1 homologues
    cd13186
    Location:207 → 296
    FERM_C_NBL4_NBL5; FERM domain C-lobe of Novel band 4.1-like protein 4 and 5 (NBL4 and 5)
    pfam00373
    Location:105 → 211
    FERM_M; FERM central domain
    pfam08736
    Location:311 → 354
    FA; FERM adjacent (FA)
    pfam09379
    Location:15 → 80
    FERM_N; FERM N-terminal domain

  3. XM_006254583.5 → XP_006254645.1  band 4.1-like protein 4A isoform X1

    See identical proteins and their annotated locations for XP_006254645.1

    UniProtKB/TrEMBL
    A0A0G2JW20, A0A8I6ATD3
    Related
    ENSRNOP00000091694.1, ENSRNOT00000099986.2
    Conserved Domains (5) summary
    smart00295
    Location:13 → 211
    B41; Band 4.1 homologues
    cd13186
    Location:207 → 296
    FERM_C_NBL4_NBL5; FERM domain C-lobe of Novel band 4.1-like protein 4 and 5 (NBL4 and 5)
    pfam00373
    Location:105 → 211
    FERM_M; FERM central domain
    pfam08736
    Location:311 → 354
    FA; FERM adjacent (FA)
    pfam09379
    Location:15 → 80
    FERM_N; FERM N-terminal domain

  4. XM_063277377.1 → XP_063133447.1  band 4.1-like protein 4A isoform X3

    UniProtKB/TrEMBL
    B5DEZ0, F1LQE5

  5. XM_039096875.2 → XP_038952803.1  band 4.1-like protein 4A isoform X3

    UniProtKB/TrEMBL
    B5DEZ0, F1LQE5
    Conserved Domains (3) summary
    cd13186
    Location:23 → 112
    FERM_C_NBL4_NBL5; FERM domain C-lobe of Novel band 4.1-like protein 4 and 5 (NBL4 and 5)
    pfam08736
    Location:127 → 171
    FA; FERM adjacent (FA)
    cl09511
    Location:2 → 27
    FERM_B-lobe; FERM domain B-lobe
Nucleotide Protein Strain
Heading Accession and Version

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