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Zfp276 zinc finger protein (C2H2 type) 276 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307924, updated on 27-Nov-2024

Summary

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Official Symbol
Zfp276provided by RGD
Official Full Name
zinc finger protein (C2H2 type) 276provided by RGD
Primary source
RGD:1307469
See related
EnsemblRapid:ENSRNOG00000016631 AllianceGenome:RGD:1307469
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in kinetochore. Orthologous to human ZNF276 (zinc finger protein 276). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 71.6), Kidney (RPKM 67.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp276 in Genome Data Viewer
Location:
19q12
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (68199709..68212757)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (51291005..51304240)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (56054250..56067767)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene cyclin-dependent kinase 10 Neighboring gene spermatogenesis associated 2-like Neighboring gene VPS9 domain containing 1 Neighboring gene FA complementation group A Neighboring gene small nucleolar RNA SNORD43 Neighboring gene spire-type actin nucleation factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. Ohta S, et al. Cell, 2010 Sep 3. PMID 20813266, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in kinetochore ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 276

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012058.2 → NP_001012058.2  zinc finger protein 276

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019
    UniProtKB/TrEMBL
    F1LN08

RNA

  1. NR_197205.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    68199709..68212757
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002728603.7 → XP_002728649.1  zinc finger protein 276

    Related
    ENSRNOP00000022324.4, ENSRNOT00000022324.8
    Conserved Domains (3) summary
    smart00868
    Location:79 → 155
    zf-AD; Zinc-finger associated domain (zf-AD)
    sd00017
    Location:467 → 487
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:493 → 515
    zf-C2H2; Zinc finger, C2H2 type

RNA

  1. XR_005496931.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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