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Nhsl1 NHS-like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308631, updated on 4-Jan-2025

Summary

Official Symbol
Nhsl1provided by RGD
Official Full Name
NHS-like 1provided by RGD
Primary source
RGD:1308124
See related
EnsemblRapid:ENSRNOG00000060603 AllianceGenome:RGD:1308124
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308124
Summary
Predicted to be involved in cell differentiation. Orthologous to human NHSL1 (NHS like 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 53.1), Heart (RPKM 31.0) and 9 other tissues See more
Orthologs
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Genomic context

See Nhsl1 in Genome Data Viewer
Location:
1p12
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (14775874..15008327)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (12956525..13188580)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (13472694..13705364)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102549233 Neighboring gene uncharacterized LOC102549339 Neighboring gene U6 spliceosomal RNA Neighboring gene large ribosomal subunit protein eL29-like Neighboring gene heme binding protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427846.1NP_001414775.1  NHS-like protein 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6JPA2
    Related
    ENSRNOP00000094113.2, ENSRNOT00000115660.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    14775874..15008327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017589823.3XP_017445312.1  NHS-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I6ASC1, A6JPA2
    Related
    ENSRNOP00000097262.1, ENSRNOT00000098675.2
  2. XM_017589824.3XP_017445313.1  NHS-like protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I5Y5X6, A6JPA2
    Related
    ENSRNOP00000077518.1, ENSRNOT00000102189.2
  3. XM_063262308.1XP_063118378.1  NHS-like protein 1 isoform X8

  4. XM_002728626.7XP_002728672.1  NHS-like protein 1 isoform X4

    See identical proteins and their annotated locations for XP_002728672.1

    UniProtKB/TrEMBL
    A6JPA2
    Conserved Domains (1) summary
    pfam15273
    Location:259889
    NHS; NHS-like
  5. XM_006227668.5XP_006227730.1  NHS-like protein 1 isoform X2

    See identical proteins and their annotated locations for XP_006227730.1

    UniProtKB/TrEMBL
    A0A0G2JZL4, A6JPA2
    Related
    ENSRNOP00000071093.2, ENSRNOT00000079250.3
    Conserved Domains (1) summary
    pfam15273
    Location:303933
    NHS; NHS-like
  6. XM_063262306.1XP_063118376.1  NHS-like protein 1 isoform X8

  7. XM_063262305.1XP_063118375.1  NHS-like protein 1 isoform X8

  8. XM_063262298.1XP_063118368.1  NHS-like protein 1 isoform X7

    UniProtKB/TrEMBL
    A6JPA2
    Related
    ENSRNOP00000102979.1, ENSRNOT00000156619.1
  9. XM_002728625.7XP_002728671.1  NHS-like protein 1 isoform X5

    See identical proteins and their annotated locations for XP_002728671.1

    UniProtKB/TrEMBL
    A0A8I6GKL0, A6JPA2
    Related
    ENSRNOP00000102281.1, ENSRNOT00000160257.1
    Conserved Domains (1) summary
    pfam15273
    Location:255885
    NHS; NHS-like
  10. XM_063262290.1XP_063118360.1  NHS-like protein 1 isoform X6

    UniProtKB/TrEMBL
    A6JPA2
  11. XM_039098789.2XP_038954717.1  NHS-like protein 1 isoform X8

    Conserved Domains (2) summary
    PHA03307
    Location:8321213
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam15273
    Location:4595
    NHS; NHS-like