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Rsf1 remodeling and spacing factor 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308839, updated on 27-Nov-2024

Summary

Official Symbol
Rsf1provided by RGD
Official Full Name
remodeling and spacing factor 1provided by RGD
Primary source
RGD:1311245
See related
EnsemblRapid:ENSRNOG00000024194 AllianceGenome:RGD:1311245
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hbxap
Summary
Predicted to enable histone binding activity and histone octamer slider activity. Predicted to be involved in several processes, including nucleosome assembly; positive regulation of viral transcription; and regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be part of RSF complex. Orthologous to human RSF1 (remodeling and spacing factor 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 93.3), Brain (RPKM 91.7) and 9 other tissues See more
Orthologs
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Genomic context

See Rsf1 in Genome Data Viewer
Location:
1q32
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (161303596..161426326)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (151892055..152015089)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (162549222..162671962)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene integrator complex subunit 4 Neighboring gene adipogenesis associated, Mth938 domain containing Neighboring gene ribosomal protein L35, pseudogene 4 Neighboring gene chloride nucleotide-sensitive channel 1A Neighboring gene aquaporin 11

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
NOT enables ATP hydrolysis activity ISO
Inferred from Sequence Orthology
more info
 
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables histone binding ISO
Inferred from Sequence Orthology
more info
 
enables histone octamer slider activity ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA-templated transcription initiation ISO
Inferred from Sequence Orthology
more info
 
involved_in chromatin organization ISO
Inferred from Sequence Orthology
more info
 
involved_in chromatin remodeling ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
involved_in nucleosome assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of viral transcription ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of RSF complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of RSF complex ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
remodeling and spacing factor 1
Names
hepatitis B virus x associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427468.1NP_001414397.1  remodeling and spacing factor 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    D3ZGQ8
    Related
    ENSRNOP00000031549.6, ENSRNOT00000037050.7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    161303596..161426326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262798.1XP_063118868.1  remodeling and spacing factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I6GKD6
    Related
    ENSRNOP00000092847.1, ENSRNOT00000098705.2
  2. XM_063262799.1XP_063118869.1  remodeling and spacing factor 1 isoform X2