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G9a - G9a

Enables histone methyltransferase activity. Involved in facultative heterochromatin formation. Located in euchromatin and polytene chromosome interband. Is active in nucleus. Is expressed in several structures, including adult brain; cystic bulge; embryonic/larval epidermis; germarium; and germline cell. Used to study Kleefstra syndrome 1 and viral infectious disease. Human ortholog(s) of this gene implicated in Kleefstra syndrome; Kleefstra syndrome 1; and idiopathic pulmonary fibrosis. Orthologous to several human genes including EHMT2 (euchromatic histone lysine methyltransferase 2). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to G9a

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Species Gene Architecture aa