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ase - asense

Enables DNA binding activity; protein heterodimerization activity; and protein homodimerization activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including Malpighian tubule development; negative regulation of mitotic nuclear division; and neuroblast fate determination. Located in nucleus. Is expressed in several structures, including ganglia; imaginal disc; presumptive embryonic/larval system; sensory nervous system primordium; and somatic precursor cell. Orthologous to human ASCL1 (achaete-scute family bHLH transcription factor 1) and ASCL2 (achaete-scute family bHLH transcription factor 2). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa