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CG17896 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 30995, updated on 9-Dec-2024

Summary

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Official Symbol
CG17896provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0023537
Locus tag
Dmel_CG17896
See related
AllianceGenome:FB:FBgn0023537
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
153323_at; Dmel\CG17896; EG:171D11.1
Summary
Predicted to enable methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity. Predicted to be involved in thymine catabolic process and valine catabolic process. Predicted to be active in mitochondrion. Is expressed in adult head; adult heart; embryonic hindgut; and organism. Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG17896 in Genome Data Viewer
Location:
1B5-1B5; 1-0 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (490787..493495, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (384820..387528, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45797 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44891 Neighboring gene uncharacterized protein Neighboring gene silver

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. GeneFizz: A web tool to compare genetic (coding/non-coding) and physical (helix/coil) segmentations of DNA sequences. Gene discovery and evolutionary perspectives. Yeramian E, et al. Nucleic Acids Res, 2003 Jul 1. PMID 12824434, Free PMC Article
  2. Identification of Drosophila MicroRNA targets. Stark A, et al. PLoS Biol, 2003 Dec. PMID 14691535, Free PMC Article
  3. X chromosome-linked intellectual disability protein PQBP1 associates with and regulates the translation of specific mRNAs. Wan D, et al. Hum Mol Genet, 2015 Aug 15. PMID 26002102
  4. Identification of Genes Involved in the Differentiation of R7y and R7p Photoreceptor Cells in Drosophila. Earl JB, et al. G3 (Bethesda), 2020 Nov 5. PMID 32972998, Free PMC Article
  5. Mass Spectrometry-Based Screening Platform Reveals Orco Interactome in Drosophila melanogaster. Yu KE, et al. Mol Cells, 2018 Feb 28. PMID 29429152, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity IEA
Inferred from Electronic Annotation
more info
  
enables methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in pyrimidine nucleobase metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in thymine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in thymine metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in valine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in valine metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG17896-PA
CG17896-PB
NP_569845.2
NP_726672.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    490787..493495 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130489.3 → NP_569845.2  uncharacterized protein Dmel_CG17896, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_569845.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O46056, Q7KW39, Q8T9I0, Q9V408
    UniProtKB/TrEMBL
    I0B1N8
    Related
    FBpp0070087
    Conserved Domains (1) summary
    cd07085
    Location:26 → 502
    ALDH_F6_MMSDH; Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2

  2. NM_166844.1 → NP_726672.1  uncharacterized protein Dmel_CG17896, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726672.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    I0B1N8
    Related
    FBpp0070088, FBtr0070093
    Conserved Domains (1) summary
    cd07085
    Location:17 → 493
    ALDH_F6_MMSDH; Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7KW39.1 Q7KW39

Gene LinkOut

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