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Hmt4-20 - Histone methyltransferase 4-20

Enables histone H4K20 trimethyltransferase activity and histone H4K20me methyltransferase activity. Involved in constitutive heterochromatin formation and retrotransposon silencing by heterochromatin formation. Located in heterochromatin and nucleus. Is expressed in organism. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 51. Orthologous to several human genes including KMT5B (lysine methyltransferase 5B). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to Hmt4-20

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Species Gene Architecture aa