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Rbf - Retinoblastoma-family protein

Enables DNA-binding transcription factor binding activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including DNA endoreduplication; negative regulation of macromolecule metabolic process; and regulation of cell cycle process. Located in chromatin and nucleus. Part of DRM complex; Myb complex; and Rb-E2F complex. Is expressed in several structures, including embryonic/larval midgut primordium; germline cell; gut section; head epidermis primordium; and mesoderm. Used to study cancer and prostate cancer. Orthologous to human RBL1 (RB transcriptional corepressor like 1) and RBL2 (RB transcriptional corepressor like 2). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa