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Larp1b La ribonucleoprotein 1B [ Rattus norvegicus (Norway rat) ]

Gene ID: 310348, updated on 27-Nov-2024

Summary

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Official Symbol
Larp1bprovided by RGD
Official Full Name
La ribonucleoprotein 1Bprovided by RGD
Primary source
RGD:1307509
See related
EnsemblRapid:ENSRNOG00000038366 AllianceGenome:RGD:1307509
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307509
Summary
Predicted to enable RNA binding activity. Orthologous to human LARP1B (La ribonucleoprotein 1B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 301.9), Testes (RPKM 268.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Larp1b in Genome Data Viewer
Location:
2q26
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (125860935..125897189)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (123936057..123969254)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (127845034..127876793)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 8 Neighboring gene FUN14 domain containing 2, pseudogene 1 Neighboring gene abhydrolase domain containing 18 Neighboring gene FUN14 domain containing 2B Neighboring gene La ribonucleoprotein 1B like Neighboring gene uncharacterized LOC134485903 Neighboring gene progesterone receptor membrane component 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Proteomic characterization of the human sperm nucleus. de Mateo S, et al. Proteomics, 2011 Jul. PMID 21630459
  2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
la-related protein 1B
Names
La ribonucleoprotein domain family, member 1B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014036.4 → NP_001014058.1  la-related protein 1B isoform 2

    See identical proteins and their annotated locations for NP_001014058.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A8I5ZVS3, A6II43, F7FP27, Q66HE8
    Conserved Domains (1) summary
    cd08038
    Location:216 → 288
    LARP_2; La RNA-binding domain of La-related protein 2

  2. NM_001415051.1 → NP_001401980.1  la-related protein 1B isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A8I5ZWA7
    Related
    ENSRNOP00000083292.1, ENSRNOT00000110414.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    125860935..125897189
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039102244.2 → XP_038958172.1  la-related protein 1B isoform X1

    Conserved Domains (1) summary
    cl02755
    Location:418 → 473
    LAM; LA motif RNA-binding domain

  2. XM_039102245.2 → XP_038958173.1  la-related protein 1B isoform X2

  3. XM_039102247.2 → XP_038958175.1  la-related protein 1B isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZVS3, A6II43, F7FP27, Q66HE8
    Conserved Domains (1) summary
    cd08038
    Location:216 → 288
    LARP_2; La RNA-binding domain of La-related protein 2

  4. XM_039102246.2 → XP_038958174.1  la-related protein 1B isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZVS3, A6II43, F7FP27, Q66HE8
    Conserved Domains (1) summary
    cd08038
    Location:216 → 288
    LARP_2; La RNA-binding domain of La-related protein 2
Nucleotide Protein Strain
Heading Accession and Version

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