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Tmem79 transmembrane protein 79 [ Rattus norvegicus (Norway rat) ]

Gene ID: 310626, updated on 2-Nov-2024

Summary

Official Symbol
Tmem79provided by RGD
Official Full Name
transmembrane protein 79provided by RGD
Primary source
RGD:1309886
See related
EnsemblRapid:ENSRNOG00000019414 AllianceGenome:RGD:1309886
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309886
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including epithelial cell maturation; establishment of skin barrier; and positive regulation of epidermis development. Predicted to act upstream of or within cornification; cuticle development; and hair follicle morphogenesis. Predicted to be located in cytoplasm. Predicted to be active in lysosomal membrane and trans-Golgi network membrane. Orthologous to human TMEM79 (transmembrane protein 79). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 73.2), Thymus (RPKM 37.8) and 6 other tissues See more
Orthologs
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Genomic context

See Tmem79 in Genome Data Viewer
Location:
2q34
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176096092..176100996, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173798267..173803151, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187701522..187706452, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ATP synthase subunit g, mitochondrial pseudogene Neighboring gene glycosylated lysosomal membrane protein Neighboring gene SMG5 nonsense mediated mRNA decay factor Neighboring gene progestin and adipoQ receptor family member 6

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC124716

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cornification ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cuticle development ISO
Inferred from Sequence Orthology
more info
 
involved_in epithelial cell maturation ISO
Inferred from Sequence Orthology
more info
 
involved_in epithelial cell maturation ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within establishment of skin barrier ISO
Inferred from Sequence Orthology
more info
 
involved_in establishment of skin barrier ISO
Inferred from Sequence Orthology
more info
 
involved_in establishment of skin barrier ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within hair follicle morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of epidermis development ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of epidermis development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulated exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulated exocytosis ISO
Inferred from Sequence Orthology
more info
 
involved_in regulated exocytosis ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
located_in lysosomal membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in trans-Golgi network membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in trans-Golgi network membrane ISO
Inferred from Sequence Orthology
more info
 
located_in trans-Golgi network membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
transmembrane protein 79
Names
mattrin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033896.1NP_001029068.1  transmembrane protein 79

    See identical proteins and their annotated locations for NP_001029068.1

    Status: PROVISIONAL

    Source sequence(s)
    BC101913
    UniProtKB/Swiss-Prot
    Q3T1H8
    UniProtKB/TrEMBL
    A6J667
    Related
    ENSRNOP00000075750.1, ENSRNOT00000092349.3
    Conserved Domains (1) summary
    pfam01124
    Location:317355
    MAPEG; MAPEG family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    176096092..176100996 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006232637.5XP_006232699.1  transmembrane protein 79 isoform X1

    See identical proteins and their annotated locations for XP_006232699.1

    UniProtKB/Swiss-Prot
    Q3T1H8
    UniProtKB/TrEMBL
    A6J667
    Conserved Domains (1) summary
    pfam01124
    Location:317355
    MAPEG; MAPEG family
  2. XM_063281835.1XP_063137905.1  transmembrane protein 79 isoform X1

    UniProtKB/Swiss-Prot
    Q3T1H8
    UniProtKB/TrEMBL
    A6J667