U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fnbp4 formin binding protein 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 311183, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Fnbp4provided by RGD
Official Full Name
formin binding protein 4provided by RGD
Primary source
RGD:1309238
See related
EnsemblRapid:ENSRNOG00000007241 AllianceGenome:RGD:1309238
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in nucleoplasm. Orthologous to human FNBP4 (formin binding protein 4). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 258.4), Spleen (RPKM 211.2) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Fnbp4 in Genome Data Viewer
Location:
3q24
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (97188852..97218916)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (76733012..76763077)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (79570610..79610122)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene nucleoporin 160 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene ribosomal protein S26, pseudogene 9 Neighboring gene AGBL carboxypeptidase 2 Neighboring gene mitochondrial carrier 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC105867

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
formin-binding protein 4

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013159.3 → NP_001013177.3  formin-binding protein 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6HN70
    Related
    ENSRNOP00000009687.8, ENSRNOT00000009687.8
    Conserved Domains (2) summary
    cd00201
    Location:604 → 635
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam00397
    Location:222 → 249
    WW; WW domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    97188852..97218916
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039104892.2 → XP_038960820.1  formin-binding protein 4 isoform X1

    Conserved Domains (2) summary
    cd00201
    Location:631 → 662
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam00397
    Location:249 → 276
    WW; WW domain

  2. XM_063283657.1 → XP_063139727.1  formin-binding protein 4 isoform X2

  3. XM_039104893.2 → XP_038960821.1  formin-binding protein 4 isoform X3

    Conserved Domains (1) summary
    pfam00397
    Location:249 → 276
    WW; WW domain

RNA

  1. XR_005501861.2 RNA Sequence

  2. XR_005501862.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools