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CG14803 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31142, updated on 4-Jan-2025

Summary

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Official Symbol
CG14803provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0023513
Locus tag
Dmel_CG14803
See related
AllianceGenome:FB:FBgn0023513
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG14803; EG:63B12.9
Summary
Predicted to be involved in double-strand break repair via homologous recombination and replication fork processing. Predicted to be active in nuclear replication fork. Is expressed in organism and spermatozoon. Orthologous to human MMS22L (MMS22 like, DNA repair protein). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG14803 in Genome Data Viewer
Location:
2B13-2B13; 1-0.2 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (1868870..1872408)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (1762903..1766441)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Germ cell nuclear acidic peptidase Neighboring gene Mediator complex subunit 18 Neighboring gene Peroxin 5 Neighboring gene Phosphoglycerate mutase 5 Neighboring gene Vacuolar protein sorting 26 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic effects in Drosophila on the potency of diverse general anesthetics: a distinctive pattern of altered sensitivity. Campbell JL, et al. J Neurogenet, 2009. PMID 19863272, Free PMC Article
  2. The Drosophila MSL complex activates the transcription of target genes. Straub T, et al. Genes Dev, 2005 Oct 1. PMID 16204179, Free PMC Article
  3. Identification of genes expressed during Drosophila melanogaster gastrulation by using subtractive hybridization. González-Agüero M, et al. Gene, 2005 Jan 31. PMID 15716118
  4. From first base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. Benos PV, et al. Genome Res, 2001 May. PMID 11337470, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
  
involved_in double-strand break repair via homologous recombination ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in replication fork processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in replication fork processing IEA
Inferred from Electronic Annotation
more info
  
involved_in replication fork processing ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in nuclear replication fork IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear replication fork ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG14803-PA
CG14803-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    1868870..1872408
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130594.2 → NP_569950.1  uncharacterized protein Dmel_CG14803, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_569950.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D0Z773, O46089, Q9W553
    Related
    FBpp0070297
    Conserved Domains (2) summary
    pfam14910
    Location:195 → 559
    MMS22L_N; S-phase genomic integrity recombination mediator, N-terminal
    pfam14911
    Location:733 → 1099
    MMS22L_C; S-phase genomic integrity recombination mediator, C-terminal

  2. NM_001297865.1 → NP_001284794.1  uncharacterized protein Dmel_CG14803, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284794.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2JA69
    Conserved Domains (2) summary
    pfam14910
    Location:190 → 554
    MMS22L_N; S-phase genomic integrity recombination mediator, N-terminal
    pfam14911
    Location:728 → 1094
    MMS22L_C; S-phase genomic integrity recombination mediator, C-terminal
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O46089.2 O46089
X2JA69 X2JA69

Gene LinkOut

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