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Btbd3 BTB domain containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 311462, updated on 4-Jan-2025

Summary

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Official Symbol
Btbd3provided by RGD
Official Full Name
BTB domain containing 3provided by RGD
Primary source
RGD:1311623
See related
EnsemblRapid:ENSRNOG00000008088 AllianceGenome:RGD:1311623
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in cerebral cortex development and dendrite morphogenesis. Predicted to be located in nucleus. Predicted to be active in cytosol. Orthologous to human BTBD3 (BTB domain containing 3). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Brain (RPKM 376.5), Lung (RPKM 217.1) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Btbd3 in Genome Data Viewer
Location:
3q36
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (146044053..146074189)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (125591427..125621660)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (131330338..131360554)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene calcineurin-like EF-hand protein 1, pseudogene 1 Neighboring gene uncharacterized LOC120101698 Neighboring gene uncharacterized LOC120101704 Neighboring gene uncharacterized LOC134486452

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. BTBD3 controls dendrite orientation toward active axons in mammalian neocortex. Matsui A, et al. Science, 2013 Nov 29. PMID 24179155
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cerebral cortex development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cerebral cortex development ISO
Inferred from Sequence Orthology
more info
  
involved_in dendrite morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in dendrite morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in neurogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
BTB/POZ domain-containing protein 3
Names
BTB (POZ) domain containing 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107782.1 → NP_001101252.1  BTB/POZ domain-containing protein 3

    See identical proteins and their annotated locations for NP_001101252.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473949
    UniProtKB/TrEMBL
    A6HQL4, D3ZJC0
    Related
    ENSRNOP00000010835.4, ENSRNOT00000010835.7
    Conserved Domains (4) summary
    smart00225
    Location:127 → 226
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00875
    Location:232 → 338
    BACK; BTB And C-terminal Kelch
    pfam00651
    Location:119 → 222
    BTB; BTB/POZ domain
    pfam08005
    Location:383 → 526
    PHR; PHR domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    146044053..146074189
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006235099.5 → XP_006235161.1  BTB/POZ domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8I6AIZ4
    Related
    ENSRNOP00000093542.1, ENSRNOT00000114685.2
    Conserved Domains (4) summary
    smart00225
    Location:60 → 159
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00875
    Location:165 → 271
    BACK; BTB And C-terminal Kelch
    pfam00651
    Location:52 → 155
    BTB; BTB/POZ domain
    pfam08005
    Location:316 → 459
    PHR; PHR domain
Nucleotide Protein Strain
Heading Accession and Version

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