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usp - ultraspiracle

Enables several functions, including core promoter sequence-specific DNA binding activity; nuclear receptor activity; and protein heterodimerization activity. Contributes to DNA-binding transcription activator activity, RNA polymerase II-specific and ecdysone binding activity. Involved in several processes, including border follicle cell migration; instar larval or pupal development; and nervous system development. Located in dendrite and nucleus. Part of activator ecdysone receptor complex. Is expressed in several structures, including adult cuticle; central nervous system; female germline cell; gland; and imaginal disc. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and pancreatic cancer. Orthologous to human RXRA (retinoid X receptor alpha); RXRB (retinoid X receptor beta); and RXRG (retinoid X receptor gamma). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa