U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zbtb43 zinc finger and BTB domain containing 43 [ Rattus norvegicus (Norway rat) ]

Gene ID: 311872, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Zbtb43provided by RGD
Official Full Name
zinc finger and BTB domain containing 43provided by RGD
Primary source
RGD:1310287
See related
EnsemblRapid:ENSRNOG00000017017 AllianceGenome:RGD:1310287
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Zfp297b
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase III general transcription initiation factor binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in membrane and nucleus. Orthologous to human ZBTB43 (zinc finger and BTB domain containing 43). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 84.7), Liver (RPKM 78.4) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Zbtb43 in Genome Data Viewer
Location:
3p11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (37142210..37161524, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (16744535..16763854, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (12489774..12509372, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene Ral GEF with PH domain and SH3 binding motif 1 Neighboring gene angiopoietin-like 2 Neighboring gene zinc finger and BTB domain containing 34 Neighboring gene uncharacterized LOC102550017 Neighboring gene small nucleolar RNA SNORA48

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase III general transcription initiation factor binding ISO
Inferred from Sequence Orthology
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger and BTB domain-containing protein 43
Names
zinc finger protein 297B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012094.1 → NP_001012094.1  zinc finger and BTB domain-containing protein 43

    See identical proteins and their annotated locations for NP_001012094.1

    Status: PROVISIONAL

    Source sequence(s)
    BC087042
    UniProtKB/TrEMBL
    A0A8I5ZT40, A0A8I6AJA1, Q5PQT4
    Related
    ENSRNOP00000022814.4, ENSRNOT00000022814.4
    Conserved Domains (3) summary
    sd00017
    Location:412 → 430
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18227
    Location:44 → 164
    BTB_POZ_ZBTB43; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 43 (ZBTB43)
    pfam13465
    Location:450 → 473
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    37142210..37161524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006233973.4 → XP_006234035.1  zinc finger and BTB domain-containing protein 43 isoform X1

    See identical proteins and their annotated locations for XP_006234035.1

    UniProtKB/TrEMBL
    A0A8I5ZT40, A0A8I6AFN4, A6JUA9
    Related
    ENSRNOP00000086987.1, ENSRNOT00000108027.2
    Conserved Domains (3) summary
    sd00017
    Location:376 → 394
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18227
    Location:8 → 128
    BTB_POZ_ZBTB43; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 43 (ZBTB43)
    pfam13465
    Location:414 → 437
    zf-H2C2_2; Zinc-finger double domain

  2. XM_006233974.4 → XP_006234036.1  zinc finger and BTB domain-containing protein 43 isoform X1

    See identical proteins and their annotated locations for XP_006234036.1

    UniProtKB/TrEMBL
    A0A8I5ZT40, A0A8I6AFN4, A6JUA9
    Related
    ENSRNOP00000096140.1, ENSRNOT00000117382.2
    Conserved Domains (3) summary
    sd00017
    Location:376 → 394
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18227
    Location:8 → 128
    BTB_POZ_ZBTB43; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 43 (ZBTB43)
    pfam13465
    Location:414 → 437
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools