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CG2854 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31219, updated on 4-Jan-2025

Summary

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Official Symbol
CG2854provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0040391
Locus tag
Dmel_CG2854
See related
AllianceGenome:FB:FBgn0040391
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG2854; EG:BACH48C10.2
Summary
Predicted to be active in mitochondrion. Orthologous to human TCAIM (T cell activation inhibitor, mitochondrial). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG2854 in Genome Data Viewer
Location:
2F6-3A1; 1-0.9 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2327128..2328941)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2221161..2222974)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Raf oncogene Neighboring gene long non-coding RNA:CR34052 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR33218 Neighboring gene Insulin-like peptide 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A fat body-derived IGF-like peptide regulates postfeeding growth in Drosophila. Okamoto N, et al. Dev Cell, 2009 Dec. PMID 20059957, Free PMC Article
  2. Phenotypic suppression of the Drosophila mitochondrial disease-like mutant tko(25t) by duplication of the mutant gene in its natural chromosomal context. Kemppainen E, et al. Mitochondrion, 2009 Sep. PMID 19616644
  3. Molecular evolution and functional characterization of Drosophila insulin-like peptides. Grönke S, et al. PLoS Genet, 2010 Feb 26. PMID 20195512, Free PMC Article
  4. A Drosophila insulin-like peptide promotes growth during nonfeeding states. Slaidina M, et al. Dev Cell, 2009 Dec. PMID 20059956, Free PMC Article
  5. The Genomic Basis of Postponed Senescence in Drosophila melanogaster. Carnes MU, et al. PLoS One, 2015. PMID 26378456, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG2854-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2327128..2328941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130643.2 → NP_569999.1  uncharacterized protein Dmel_CG2854 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_569999.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0N0, Q9W4Z5
    Related
    FBpp0070383, FBtr0070399
    Conserved Domains (2) summary
    pfam14687
    Location:15 → 117
    DUF4460; Domain of unknown function (DUF4460)
    pfam14688
    Location:181 → 486
    DUF4461; Domain of unknown function (DUF4461)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W4Z5 Q9W4Z5

Gene LinkOut

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