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per - period

Predicted to enable transcription cis-regulatory region binding activity and transcription corepressor binding activity. Involved in several processes, including circadian temperature homeostasis; determination of adult lifespan; and regulation of gene expression. Located in cell body; cytoplasm; and nucleus. Is expressed in several structures, including epithelium; larval CNS neuron; longitudinal vein; organism subdivision; and pacemaker neurons. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome (multiple); alcohol dependence; bipolar disorder; cocaine dependence; and fetal alcohol spectrum disorder. Orthologous to several human genes including PER1 (period circadian regulator 1) and PER3 (period circadian regulator 3). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa