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CG3603 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31289, updated on 4-Jan-2025

Summary

Official Symbol
CG3603provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0029648
Locus tag
Dmel_CG3603
See related
AllianceGenome:FB:FBgn0029648
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH09070; Dmel\CG3603
Summary
Predicted to enable 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity and quinone binding activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to be located in mitochondrial matrix. Is expressed in adult head; adult heart; and organism. Orthologous to human HSD17B8 (hydroxysteroid 17-beta dehydrogenase 8). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See CG3603 in Genome Data Viewer
Location:
3C3-3C3; 1-2 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2948034..2949120)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2842067..2843153)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene kin of irre Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene roughest Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
 
enables quinone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in mitochondrial matrix ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
uncharacterized protein
Names
CG3603-PA
CG3603-PB
NP_001259199.1
NP_570046.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2948034..2949120
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272270.1NP_001259199.1  uncharacterized protein Dmel_CG3603, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259199.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B4F625, Q9W4U2
    Conserved Domains (2) summary
    cd05333
    Location:9248
    BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs
    PRK05653
    Location:6248
    fabG; 3-ketoacyl-(acyl-carrier-protein) reductase; Validated
  2. NM_130690.3NP_570046.1  uncharacterized protein Dmel_CG3603, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_570046.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B4F625, Q9W4U2
    Related
    FBpp0070533
    Conserved Domains (2) summary
    cd05333
    Location:9248
    BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs
    PRK05653
    Location:6248
    fabG; 3-ketoacyl-(acyl-carrier-protein) reductase; Validated