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Myc - Myc

Enables DNA binding activity; DNA-binding transcription factor activity; and ubiquitin-specific protease binding activity. Involved in several processes, including DNA endoreduplication; positive regulation of developmental growth; and positive regulation of macromolecule biosynthetic process. Located in nucleus. Part of protein-containing complex. Colocalizes with histone locus body. Is expressed in several structures, including anlage in statu nascendi; cuboidal/columnar epithelium; embryonic/larval midgut primordium; germ layer; and gut section. Used to study brain cancer and cancer. Human ortholog(s) of this gene implicated in several diseases, including angiosarcoma; carcinoma (multiple); demyelinating disease; hematologic cancer (multiple); and prostate cancer (multiple). Orthologous to human MYC (MYC proto-oncogene, bHLH transcription factor). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to Myc

NCBI Orthologs

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Species Gene Architecture aa